This study aims to establish the etiological distribution of Anterior Uveitis at a tertiary care centre at Tamilnadu. Study: A Prospective Descriptive type of observational study. Material and Methods:72 patients presented to the Department of Ophthalmology at Rajah Muthiah Medical College and Hospital, who had been diagnosed with a clinical diagnosis of Anterior Uveitis were examined clinically with a slit lamp and binocular Indirect ophthalmoscopy Patients were investigated appropriately with a follow up period of 6 months. Results: Out of 72 patients diagnosed with Anterior Uveitis, 43.1% of Study Population were diagnosed as having idiopathic etiological factor. 30.6% of the population was affected by Traumatic Iridocyclitis. Followed by Post operative uveitis accounting 8.3% study population. Various other etiology including COVID vaccination, Scrub typhus and Metastasis from breast cancer had also been described in this study. Though HLA-B27 association was common in other studies, in this study 2.8% of the study population were affected. Conclusion:In case of Anterior uveitis, it is vital to evaluate the patient systematically as most often patient have an etiological factor has been associated with either an autoimmune condition or an infectious etiology. Recurrences can be prevented on detecting and treating the systemic association.