We derive a simple analytical formula for the low field electron mobility which uses the 2-d degenerate statistics of the 2-d electron gas. This takes into account the finite width of the depletion layer in (Al,Ga)As for the scattering by remote donors, scattering by the interface charge, and the polar-optical and acoustic deformation potential and piezoelectric scattering. The largest measured value of mobility is determined by scattering due to interface charge in some cases. The ultimate value of the mobility which may be achieved is limited by the acoustic deformation potential and piezoelectric scattering at about 6.5×106 cm2/V s for an interface carrier density of the 2-d electron gas ns0 ≂4×1011 cm−2. Our results agree very well with experimental data obtained in our laboratory as well as other laboratories.

No abstract

No abstract

Pharmacogenetic research has historically lacked racial and ethnic diversity, limiting the application of findings to minority populations. Recent studies, including the Hmong, have gauged communities' interest in participating in genomic research and receiving their individual results. This study was conducted to create a culturally and linguistically appropriate format to return pharmacogenomic results and identify Minnesota Hmong research participants' reactions to their personal and collective results. Using a community-based participatory research approach, researchers collaborated with Hmong community members to format the pharmacogenetic disclosure process. Three focus groups were completed with 24 Hmong participants and three major themes emerged using thematic analysis. Many Hmong focus group participants viewed the results positively, finding them useful for themselves and their community as a means to optimize responses to and avoid harms from medicines. However, some participants expressed concerns about harms that the pharmacogenetic information could bring, including anxiety, misunderstanding, discrimination, exploitation, and lack of a clinician involvement in interpreting and applying the result. Many participants interpreted their results through an experiential lens, trusting their experience of medicines more than trusting genetic information, and through a cultural lens, expressing the belief that environmental factors may influence how people's bodies respond to medicines by influencing their inherited flesh and blood (roj ntsha). Lastly, participants stressed the importance of disseminating the information while acknowledging the complex linguistic, educational, and cultural factors that limit understanding of the results. Researchers, genetic counselors, pharmacists, and healthcare providers should strive to return results in meaningful ways to all members of society.

No abstract