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Group. -Along with their synthesis, the results of studies on the insecticidal activity of a few new oxadiazole derivatives, e.g. (III), are reported. (IIIb) and (IIIc) show low insecticidal activity against A. craccivora. -(MOHAN, T. P.; VISHALAKSHI*, B.; BHAT, K. S.; RAO, K. S.; KENDAPPA, G. N.; Indian J.

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in the N 1 -benzenesulfonamide ring of celecoxib are performed. The series with a hydroxymethyl group adjacent to the sulfonamide is found to be the most potent modification that provides many compounds selectively active against COX-2 enzyme in vitro. -(SINGH*, S. K.; REDDY, P. G.; RAO, K. S.; LOHRAY, B. B.; MISRA, P.; RAJJAK, S. A.; RAO, Y. K.; VENKATESWARLU, A.; Bioorg. Med. Chem. Lett. 14 (2004) 2, 499-504; Chem. Discovery Res., Dr. Reddy's Lab. Ltd., Hyderabad 500 050, India; Eng.) -A. Forchert 16-123

A simple, efficient, regioselective and diastereoselective method has been developed for the synthesis of spirooxindole-pyrrolidines using 0.5 mol% of ceric ammonium nitrate in aqueous medium.