of tubal occlusion in women with infertility, analysing studies that used laparoscopic tubal chromoperturbation dye test as the reference standard. Methods: Studies assessing 2D and 3D/4D HyCoSy for the assessment of tubal occlusion in women with infertility from January 1990 to April 2019 were searched using Medline and Web of Science databases by three authors, using the terms: ''hysterosalpingocontrast-sonography'', ''sonohysterosalpingography'', ''HyCoSy'', ''HyFoSy'', ''three-dimensional'', ''four-dimensional'', ''ultrasound'', ''tubal patency'' and ''tubal occlusion''. Quality was assessed using QUADAS-2 tool. Results: 30 articles were included: 21 studies used 2D HyCoSy to assess tubal occlusion, six used 3D/4D HyCoSy, one study used both techniques but in different set of patients and two used both techniques in the same patients. The risk of bias for most studies was low as assessed in QUADAS-2, except for patient selection domain. Overall, pooled estimated sensitivity and specificity of 2D HyCosy were 86% (95% CI = 80%-91%) and 94% (95% CI = 90%-96%), respectively. These figures were 95% (95% CI = 89%-98%) and 89% (95% CI = 82%-94%) for 3D/4D HyCoSy. High heterogeneity was found for both sensitivity and for specificity among studies. No statistical differences were found between methods (p = 0.13). Conclusions: We concluded that 2D HyCoSy has a similar diagnostic performance than 3D/4D HyCoSy. VP64.07 Is I-shaped uterus more common in patients with hyperandrogenism?
index (FI) and vascular flow index (VFI) of the fibroid, the vascular capsule and of its highest vascular area, using both manual and automatic contour modes. The intraclass correlation coefficient and discriminating values were calculated. The correlation between VI and volume was studied using Kendall's Tau test. Results: In the manual contour mode, the VI of the fibroid and of the vascular capsule had the highest interobserver agreement (ICC 0.89 and 0.87, respectively). Both parameters seem to have good discriminating values, given the large range of these parameters between different fibroids, independent of their volume. The vascularity of the fibroid and capsule were related. VI was not related to the volume of the fibroid. Conclusions: VI assessed using 3D PDUS is a reproducible parameter in the assessment of fibroid vascularization with discriminating abilities. Additional studies are needed to further evaluate validity and its clinical relevance.Supporting information can be found in the online version of this abstract Objectives: To assess user satisfaction with the Clinical Data Miner (CDM) software, used for collecting data for the International Endometrial Tumor Analysis (IETA) studies. Methods: We created an anonymous survey on http://www. surveymonkey.com. It first measures agreement, on a scale of zero to ten, with statements regarding user satisfaction. A second part quantifies the frequency of issues experienced by users.We sent the survey to users who had submitted at least 10 patient entries to the IETA studies, or who previously participated in an inter-rater agreement study organized using CDM. Selected participants thus had a certain level of CDM experience, ensuring meaningful results. Results: Of 42 selected users, 28 responded (66.7% response rate). User-friendliness of CDM's Visual Analogue Scale obtained the lowest average agreement (8.1), while the clarifying nature of the pictograms integrated in the user interface obtained the highest (9.4). CDM's user-friendliness was rated at 8.6. Most users (78.6%) experienced issues with CDM less than 5% of the time. Comprehensive results are available from https://www. surveymonkey.com/results/SM-QDYK9B7. Conclusions: CDM user satisfaction is very high. Most users experience relatively few issues. Users particularly like the integration of pictograms in CDM's user interface, and all responders would consider using CDM for their own studies.Supporting information can be found in the online version of this abstract Objectives: Abnormal Uterine Bleeding (AUB) above the age of 40 is a common complaint in gynecology. Endometrial Office Biopsy (EOB) is the primary method used to detect endometrial pathology. The objective of this study is to evaluate the effectiveness of three-Dimensional Saline Infusion Sonohysterography Guided Biopsy (3D SISHGB), as compared with EOB in diagnosing endometrial pathologies, (histological and anatomical) among peri-menopausal and post-menopausal women with abnormal uterine bleeding. Methods: It is an interventional ...