Systemic lupus erythematosus (SLE) is an autoimmune disease most frequently found in women of childbearing age and may coexist with pregnancy. Disease exacerbation, increased fetal loss, neonatal lupus, and an increased incidence of preeclampsia are the major challenges. Its multisystem involvement and therapeutic interventions like anticoagulants, steroids, and immunosuppressive agents pose a high risk for both the mother and the fetus during the antenatal period as well as postpartum. Good multidisciplinary medical care is mandatory when detection or flare-up of SLE occurs during pregnancy.We describe the successful management of an antinuclear antibody, antiribonucleoprotein antibody, and anti-Sjogren's syndrome A (Ro) antibody positive parturient with bad obstetric history who underwent elective cesarean section and delivered a healthy child.

To compare the biochemical and haematological markers in pre¬ eclampsia and eclampsia patients with normal pregnancies. Standard antenatal follow up should be carried out for the early detection and prevention of PIH. Tests like serum LDH, uric acid and alkaline phosphatase could help to predict and to deal with the adverse complications of PIH, which are considered as cost effective as these tests are routinely done in most of the laboratories. The fact that hypertension in pregnancy is largely a preventable condition is established by observing the negligible incidence of pre eclampsia and eclampsia with the institution of early management. In present study, we observed a specific pattern of disease and its related variation with these markers. Simple markers like LDH, Uric acid, Platelet count, Alkaline phosphatase, PTT and aPTT are the early predictors of the maternal and fetal outcome .The early detection of compromised status combined with the institution of prompt treatment has been proven to have a crucial and definite role in reducing the morbidity and mortality of both mother and fetus.