High acceptance of COVID-19 vaccines is crucial to ending the COVID-19 pandemic. Healthcare workers (HCWs) are frontline responders in the fight against COVID-19, they were prioritized to receive the COVID-19 vaccine in Nigeria. This study assessed the acceptance of the COVID-19 vaccine among HCWs in Katsina State using an online structured questionnaire and predicted variables that could increase the acceptance of the vaccine among HCWs using logistic regression analysis. A total of 793 HCWs were included in this study. Of these, 65.4% (n=519) of them were male and 36.2% (n=287) were aged between 30-39 years. Eighty percent (80%, n=638) of the HCWs have been tested for the SARS-CoV-2 out of which 10.8% (n=65) of them tested positive. The majority of the HCWs (97.3%, n=765) believed that the COVID-19 vaccine was safe and 90% (n=714) of the HCWs have received the first dose of the COVID-19 vaccine. Our findings showed that the age of the HCW, their COVID-19 testing status, and the type of health facility they work (either public or private) were the main predictors for the acceptance of the COVID-19 vaccine among HCWs in Katsina state. HCWs between the age of 30-39 years were more likely (OR:7.06; 95% CI: 2.36, 21.07; p < 0.001) to accept the vaccine than others. In the same vein, HCWs that have been tested for COVID-19 were more likely (OR:7.64; 95% CI: 3.62, 16.16; p < 0.001) to accept the vaccine than those that have not been tested. In addition, HCWs in public health facilities were more likely (OR: 2.91; 95% CI: 1.17, 6.11; p = 0.094) to accept the COVID-19 vaccine than their counterparts in private health facilities. There was a high acceptance of the COVID-19 vaccines among HCWs in Katsina State. More emphasis should be paid on adherence to non-pharmaceutical interventions and the availability of vaccines for HCWs in private hospitals.

ObjectiveDespite the increasing disease burden, there is a dearth of context-specific evidence on the risk factors for COVID-19 positivity and subsequent death in Nigeria. Thus, the study objective was to identify context-specific factors associated with testing positive for COVID-19 and fatality in Nigeria.DesignRetrospective cohort study.SettingCOVID-19 surveillance and laboratory centres in 36 states and the Federal Capital Territory reporting data to the Nigeria Centre for Disease Control.ParticipantsIndividuals who were investigated for SARS-CoV-2 using real-time PCR testing during the study period 27 February–8 June 2020.MethodsCOVID-19 positivity and subsequent mortality. Multivariable logistic regression analyses were performed to identify factors independently associated with both outcome variables, and findings are presented as adjusted ORs (aORs) and 95% CIs.ResultsA total of 36 496 patients were tested for COVID-19, with 10 517 confirmed cases. Of 3215 confirmed cases with available clinical outcomes, 295 died. Factors independently associated with COVID-19 positivity were older age (p value for trend<0.0001), male sex (aOR 1.11, 95% CI 1.04 to 1.18) and the following presenting symptoms: cough (aOR 1.23, 95% CI 1.13 to 1.32), fever (aOR 1.45, 95% CI 1.45 to 1.71), loss of smell (aOR 7.78, 95% CI 5.19 to 11.66) and loss of taste (aOR 2.50, 95% CI 1.60 to 3.90). An increased risk of mortality following COVID-19 was observed in those aged ≥51 years, patients in farming occupation (aOR 7.56, 95% CI 1.70 to 33.53) and those presenting with cough (aOR 2.06, 95% CI 1.41 to 3.01), breathing difficulties (aOR 5.68, 95% CI 3.77 to 8.58) and vomiting (aOR 2.54, 95% CI 1.33 to 4.84).ConclusionThe significant risk factors associated with COVID-19 positivity and subsequent mortality in the Nigerian population are similar to those reported in studies from other countries and should guide clinical decisions for COVID-19 testing and specialist care referrals.

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