This review aims to characterize the dualistic role of autophagy in both the suppression and propagation of carcinogenesis. The process of autophagy is responsible for maintaining the delicate balance between the survival and death of a cell, and in the past years it has been studied profoundly. It has been proven that the role of autophagy in maintaining genomic and structural integrity can lead to the suppression of carcinogenesis in its early stages. However, once carcinogenesis has occurred, the process of autophagy may contribute to the survival of tumor cells and, consequently, lead to tumor progression. Additionally, autophagy can modulate the response of the tumor cells to therapy, leading to radiotherapy and chemotherapy resistance or reduced susceptibility to anticancer drugs that propagate autophagy-related cell death. Although the role and course of autophagy are not yet fully known, the essence of it seems to be within our grasp. We have observed the identification of an increasing number of autophagy-related genes (ATG). Therefore, more research concerning its molecular course and potential applications in cancer treatment and prevention needs to be conducted.

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Proper diet is a well-established factor influencing the effectiveness of training. to assess the knowledge of young sportspeople from Wrocław about sport nutritional strategies an online survey was distributed to Wrocław sport schools and clubs. the respondents were asked to answer questions regarding their sport activity, diet and the knowledge of nutrition strategies. the answers were then compared with the recommended strategies of international Society of Sports Nutrition (iSSN) and other research on this topic. 147 answers were analyzed. 38% of the respondents modified their diet due to training. their most popular strategy was an additional pre-workout meal. in the group that did not modify the diet, the majority (82%) heard of some sport nutrition strategy. 52% of the respondents consumed a protein peri-workout meal. estimated 30% consume the amount of protein recommended by iSSN. Percentage of young sportspeople adjusting diet to training seems to be low, taking into account both established importance of such proceedings and awareness of sport nutrition strategies in this group. interestingly, more men than women do so. Group of respondents following well-documented iSSN recommendations is comparably modest. Perhaps the topic of nutrition strategies should be given more emphasis in schools and sport associations.

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