Background: Iron deficiency anaemia is a common problem in antenatal patient especially in primigravida in developing world. The study was conducted to evaluate the efficacy of intravenous iron sucrose in antenatal primigravida anaemic cases. Aims and Objectives: The study was conducted to evaluate the response of intravenous iron therapy in anaemic antenatal primigravida patients. The rise of hemoglobin level was predicted after therapy. Materials and Methods: A prospective cross-sectional study was done in the antenatal clinic of Popular Medical College Hospital from January 2016 to December 2016. Primigravida women of e” 18 years with iron deficiency anaemia were included in this study. Pretreatment hemoglobin level was measured. After total dose of calculated iron, intravenous iron sucrose was infused to achieve the target hemoglobin. After completion of therapy hemoglobin was measured 2 weeks and 4 weeks after last dose of iron treatment. Mean, percentage, Chi-square test was done and P value <0.05 was considered significant. Results: Among the 63 primigravida anaemic patients mean age of the study subjects were 23.98 years with mean gestational age were 23.54 weeks. Their pretreatment hemoglobin level was 5.42 gm/dl. After total dose infusion of iron sucrose, the mean rise of hemoglobin after 2 weeks was 8.87 gm/dl and after 4 weeks was 10.87 gm/dl respectively. This findings were statistically significant (P<0.001). Attainment of target hemoglobin at the range of 9.1-11.0 gm/ dl was 50.79% and 65.08% after 2 weeks and 4 weeks respectively. Conclusion: Parenteral iron therapy in the form of iron sucrose proved to be better choice to correct iron deficiency anaemia in primigravida anaemic patients J Dhaka Medical College, Vol. 27, No.1, April, 2018, Page 79-82

A 33 years old lady presented with history of irregular menstrual cycle followed by menorrhagia. USG revealed left ovarian solid mass but all tumor markers were within normal range. A solid mass on left sided ovary was found on laparotomy. Histopathological examination of the mass showed well differentiated sertoli cell tumor. Tumors of the stroma (Leydig cells) and/or sex cords (Sertoli cells) represent approximately 8% of ovarian tumors and develop from the connective tissue (respectively, interstitial and nurse cells) of the ovary. Because these cells participate in ovarian hormonal function, most of the sex-cord or stromal tumors are able to secrete hormones (estrogens, androgens, corticoids), which explains the hormonal dysfunctions associated with these tumors. Their prognosis are difficult to establish; some of the tumors are almost always benign (Sertoli cell tumors, Leydig cell tumors), whereas others are malignant but with more-or-less delayed local-regional or metastatic relapses.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 54-56

Gonadal dysgenesis is a rare cause of primary amenorrhoea ,which is a relatively common problem among teenage girls.Primary amenorrhoea occurs in patient with gonadal dysgenesis because of absence or limited ovarian function due to inappropriate development.Streak gonads are unable to produce estrogens and/or androgens,resulting in minimal to no development of secondary sexual characteristics.Adrenal androgens may induce production of pubic hair,but patient will have minimal breast development.These patients may have a family history of infertility, short stature,sensorineural deafness,ataxia,mild mental retardation or gonadoblastoma. Here two cases of primary amenorrhoea due to pure gonadal dysgenesis are presented. 1 st  one was a 18yr old girl whose mother consulted with a gynaecologist at the age of 16yr because of her worries about absence of menarche of her daughter and secondone was a 14yr old girl whose mother consulted with a gynaecologist at the age of 16yr because of absence of secondary sexual characteristics as well as menarche of her daughter. In both cases, blood test showed very high levels of follicle stimulating hormone (FSH) & luteinizing hormone (LH), low levels of oestradiol& very low level of AMH. USG findings of both cases showed a bit hypoplastic uterus and volume of ovaries were smaller than normal. A diagnostic laparoscopy with biopsy of both gonads of one case was performed.Another case did not give consent for laparoscopy.Hormonal replacement therapy was applied on them for establishment of normal menstruation and menstruation was established in both cases.  An early diagnosis is extremely important to prevent long term consequences of Gonadal dysgenesis.J Bangladesh Coll Phys Surg 2018; 36(4): 170-174