Objective: To compare social characteristics, risk behaviors, and sexually transmitted infections among travestis and transsexual women. Methodology: A cross-sectional study was carried out in three cities in Goiás, Central Brazil. Trans women were interviewed on sociodemographic characteristics, discrimination, prejudice, sexual behavior, illicit drugs, and previous testing for HIV and syphilis between April 2018 and August 2019. Results: A total of 166 travestis and 249 transsexual women were investigated. Although sexual, physical, and verbal violence were common to both groups, sexual behavior, use of illicit drugs, prison, and previous positive HIV and syphilis testing were more frequent among travestis than in transsexual women. Conclusion: The present findings confirm that Brazilian travestis are at greater risk for sexually transmitted infections (STI), indicating that health services should take this imbalance into account in terms of health intervention proportions.

The coronavirus disease 2019 (COVID-19) pandemic has changed the course of human history and killed millions of people worldwide. Its long-term consequences remain uncertain. This study aimed to describe the short- and long-term symptoms of COVID-19 among individuals in Goiás, central Brazil, who experienced acute mild or non-symptomatic SARS-CoV-2 infection during the first wave of the pandemic. This prospective cohort study included 110 healthcare workers, 18 safety workers, and 19 administrative support workers, who were followed up for 12 months after the onset of COVID-19. Most participants were healthy adult female healthcare professionals. At the onset of infection, the major symptoms were headache, myalgia, nasal congestion, cough, coryza, anosmia, ageusia, sore throat, fatigue, diarrhea, and dyspnea. Furthermore, 20.3% of the participants had three or more COVID-19 symptoms that persisted for at least 12 months. These included coryza, congestion, hair loss, sore throat, headache, myalgia, cough, memory loss, anosmia, and fatigue. This study revealed a high prevalence of persistent symptoms of COVID-19 in healthy individuals from central Brazil, which may present an additional burden on healthcare services. Further studies are required to investigate the sequelae of COVID-19 over periods greater than 12 months.

Justificativa e objetivos: Infecções do trato urinário de origem comunitária em idosos são frequentes. O estudo objetivou avaliar a prevalência e a evolução da resistência das bactérias gram-negativas de infecção comunitária do trato urinário em idosos. Métodos: Estudo transversal, dividido em dois períodos 2011-2012 e 2013-2015, realizado no município de Goiânia, Goiás, de 2011 a 2015, com a participação de quatro laboratórios clínicos. Todos os relatórios positivos de urocultura com o respectivo antibiograma foram considerados. Apenas o primeiro laudo de exame de cada paciente foi incluído na análise, a menos que a reinfecção ocorra três meses após a primeira. Resultados: Foram analisados 3.388 antibiogramas. Os microrganismos mais frequentemente isolados foram sucessivamente E. coli (75,6%), K. pneumoniae (16,6%) e Proteus spp. (5,7%). E. coli apresentou alta taxa de resistência à Sulfonamida (40,5%), Ciprofloxacina (35,0%) e aumento da resistência as Cefalosporinas de 2ª Geração (p = 0,007). As maiores taxas de resistência em K. pneumoniae foram para Sulfonamida (35,2%), Nitrofurantoína (37,9%), Gemifloxacina (46,1%) e Ofloxacina (46,1%) com aumento da evolução da resistência aos carbapenems (p = 0,03) e Cefalosporinas da 1ª Geração ( P = 0,049). Para Proteus spp., a maior resistência foi para Gemifloxacina (46,11%), Ofloxacina (46,11%), Nitrofurantoína (76,68%) e Levofloxacina (81,87%). Enterobacter spp., resistência à Gemifloxacina (42,9%), Ofloxacina (42,9%), Cefalosporinas da 1ª Geração (44,3%) e Levofloxacina (77,1%), com evolução da resistência à Cefalosporina de 2ª geração (p = 0,0057). Conclusão: A prevalência da resistência bacteriana foi elevada para os principais antimicrobianos testados e foi identificada tendência para o aumento da resistência entre os microrganismos analisados. DESCRITORES: Infecções Bacterianas. Infecções por Enterobacteriaceae. Agentes Antimicrobianos. Sistema Urinário. Escherichia coli.

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Background: Transgender women (TGW) are susceptible to the acquisition of sexually transmitted infections (STIs), including human papillomavirus (HPV). Nonetheless, the exact data for this population are scarce. We estimated HPV positivity at the anal, genital, and oral sites among TGW and also identified the related characteristics and behaviors that could be risk factors for HPV infection in a sample of TGW in Brazil. Furthermore, we characterized the site-specific HPV genotypes among those who were positive for HPV at these 3 sites. Methods:A cross-sectional study was conducted on TGW in Goiânia City (Central-Midwest region), Brazil, between April 2018 and August 2019. Respondent-driven sampling was applied for recruitment. Next, self-collected anal, genital, and oral samples were examined for HPV DNA using polymerase chain reaction (SPF-10 primer). Human papillomavirus genotypes were identified in 12 TGW. Results:In the TGW included in the study, the anal, genital, and oral HPV positivity values were 77.2% (95% confidence interval [CI], 67.3%-84.6%), 33.5% (95% CI, 26.1%-48.9%), and 10.9% (95% CI, 5.8%-17.0%), respectively. In addition, the majority of 12 participants who tested for HPV had multiple genotypes. HPV-52 was the most prevalent genotype identified at the anal (66.6%) and genital (40.0%) sites, whereas HPV-62 and HPV-66 were the most common at the oral site (25.0%).Conclusions: A high HPV positivity was observed among TGW. Therefore, additional epidemiological studies on HPV genotypes should generate health intervention information, including the prevention, diagnosis, and treatment of sexually transmitted infections.H uman papillomavirus (HPV) is the most prevalent sexually transmitted pathogen globally. High-risk HPV genotypes are responsible for almost all cases of cervical cancer and several other anogenital, head, and neck cancers. 1,2 Annually, HPV accounts for 60,000 and 570,000 cases of cancers (including anal, penile, cervical, vaginal, vulvar, and oropharyngeal cancers) in men and women worldwide, respectively. Despite the availability of vaccines against HPV since 2006, cancers related to this virus continue to be a significant cause of morbidity and mortality in several regions worldwide, particularly in less developed countries. 1,3 It is interesting that an estimated 0.69% of the adult population in Brazil identifies as transgender, which represents approximately 1,090,200 Brazilians. 4 Transgender women (TGW) are vulnerable to the acquisition of sexually transmitted infections (STIs), including HPV; nonetheless, the precise data for this population are scarce. [5][6][7] Previous studies reported that the prevalence of HPV infection in TGW ranged from 77.9% to 97.4% for the anal area, 88.3% for anogenital HPV, and 9.1% for the oral cavity. [6][7][8] Only one study had previously reported a prevalence of 77.9% for anal HPVamong TGW in Brazil and identified HPV-16 as the most frequent genotype. 6 Nonetheless, no studies in Brazil have investigated HPV at 3 sites (anal, genital, and oral...