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Drug information service gains its importance as the development of new drugs and new diseases rising in no time and on other side the limited availability of health care resources to provide factual information in handling the new diseases and drugs. The aim of this study is to provide relevant information to the queries and evaluate the quality of the services provided. Prospective analysis was done for a period of 6 months in a south Indian tertiary care teaching hospital. We have interacted directly with health care professional to obtain queries and also communicated them with query boxes. In prospective analysis, A total of 108 queries were responded and identified 31 medication errors among them ,almost 65 % were rectified, 25 % were accepted but could not rectify as prescribers have justified the reason and remaining 10 % were not accepted as an error. 49 % of the requesters were appreciated with good; only 3% were advised to improve the quality. It was found that, the quality of the drug information service is "well accepted" and provides a great opportunity for further improvement with the involvement of more number of healthcare professionals.

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