The aim of this study was to conduct a bibliometric analysis of the scientific articles on advanced glycation end products (AGEs) and obesity. English-language journal articles about AGEs and obesity were retrieved from the Scopus database. The OpenRefine application was used for data cleaning, the VOSviewer software program for analysis of the trends of year of publication, country, institution, journal, authors, references, and keywords. Microsoft Excel and Tableau Public were applied for the visualizing of the publication trends. Data collection was performed on 3 February 2022, from a total of 1170 documents. The Mann–Whitney test and Spearman test with software SPSS ver.28.0.1.1. were used to assess the relation between open access journal statuses, years of publications, and CiteScore. The results of the study showed that there was an increase in studies on processed foods, including AGEs and obesity. The United States was the country with the largest contribution in this field, with the highest number of citations. The Nutrients journal published the largest number of articles on this topic, particularly in the last two years. The present focus of the studies is on ultra-processed foods. The open access journals have younger medians of the year of publication and higher medians for number of citations than do closed access journals (p < 0.001 and p < 0.05, respectively). A strong negative association was seen between CiteScore and the year of publication (r = −0.64 [95%CI: −0.67, −0.60]), p < 0.001. We present this bibliometric analysis to furnish the most recent data on the description, visualization, and analysis of AGEs and obesity.

Depression is one of the major problems, and the prevalence is higher among the elderly. The underlying mechanism of depression among this set of the population is multifactorial, and one of the most important factors in the pathophysiology of depression is the level of brain serotonin. Protein deficiency is linked to tryptophan deficiency that is known to be the essential material for the synthesis of serotonin. This randomized controlled trial looked for the effectiveness of eel’s head powder administration on plasma tryptophan level and geriatric depression scale (GDS) scores among the elderly population who suffered from depression. The subjects were divided into three intervention groups, including groups that were given 2-week course of 5 mg/kg BW eel’s head powder, 10 mg/kg BW eel’s head powder, and placebo, respectively. There was a significant difference in plasma tryptophan level and geriatric depression scale between the 10 mg/kg BW group and 5 mg/kg BW group. There was also a significant difference between those given 10 mg/kg BW eel’s head powder and those receiving placebo; however, no such difference was found between those in the 5 mg/kg BW eel’s head powder group and placebo group. Eel’s head powder administration could increase plasma tryptophan level and reduce geriatric depression scale score among older individuals who suffered from depression. Administration of 10 mg/kg BW eel’s head powder was significant in increasing plasma tryptophan level and reducing GDS score.

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