A group of 210 patients with total maxillary and mandibular prostheses were examined to identify the main pathological alterations suffered by edentulous patients. The observed results determined that the average age at which the largest edentulous population is found is between 56 and 65 years with a higher prevalence of females. Of these more than 50% have used oral prostheses for more than 12 years with an adequate hygiene quality in 116 patients where the most frequent oral pathology associated with edentulism was fibrous hyperplasia (epulis), found in 19 patients, followed by stomatitis sub-prosthesis.Resumen: Se examinó a 210 pacientes portadores de prótesis total maxilar y mandibular para identificar las principales alteraciones patológicas que padecen los pacientes edentulos. Los resultados observados determinaron que el promedio de edad donde se encuentra la mayor población edéntula ocurre entre los 56 y 65 años con una prevalencia mayor en el género femenino, de estos más del 50% han empleado prótesis bucales por más de 12 años con una calidad en la higiene adecuada en 116 pacientes donde la patología bucal más frecuente asociada al edentulismo fue la hiperplasia fibrosa (épulis) en 19 de ellos seguida por la estomatitis subprotésica.

Background: Pyogenic granuloma is a kind of inflammatory hyperplasia of multifactorial origin. It is usually related to trauma or constant irritation, drug use and hormonal factors, among others. On the other hand, the odontoma is a benign odontogenic tumor composed of epithelial and mesenchymal cells. Its development is usually associated with trauma, infections, inherited disorders or odontoblast hyperactivity. Objective: To present the clinical case of a patient with pyogenic granuloma associated with the presence of a mandibular odontoma, its therapeutic management and postoperative results. Case report: The case presents a 32-year-old female patient with a history of multinodular goiter and hypothyroidism who developed a mandibular odontoma on the left side, which was also associated with a pyogenic granuloma in the same area. It was treated with surgical excision and the affected tissues were reconstructed with lyophilized bone and collagen membrane. Favorable outcome was seen after surgery without evidence of recurrence and with proper osseointegration of alloplastic materials and soft tissues. Conclusions: The irritant effect of a tumor (odontoma) in developing a pyogenic granuloma was confirmed.