One of the most effective treatments for diabetes mellitus is to inhibit α-glucosidase, which inhibits glucose absorption by the epithelium membrane of the small intestine. In South Sulawesi, Indonesia, Merremia vitifolia is used as a traditional medicine for the treatment of diabetes.  The aims of this study are to (1) assess the extract's ability to inhibit α - glucosidase and (2) identify volatile organic compounds in n-hexane of Merremia vitifolia extract. Extraction was conducted by maceration.  The inhibitory activity of quercetin towards α-glucosidase has the IC50 = 2.53 ± 0.16 µg/mL, and by n-Hexane extract of Merremia vitifolia leaves has the IC50 = 14.4 ± 1.52 µg/mL.  Then, n-Hexane extract of Merremia vitifolia leaves has strong α-glucosidase inhibitory activity. The compounds that have been identified based on Gas Chromatography-Mass Spectrometry (GC-MS) analysis with similarity index ≥ 89% which are caryophyllene (0.94%), (E)-β-famesene (4.72%), neophytadiene (9.78%), phytol (65.94%), 9,12,15-octadecatrienoic acid (6.71%), 1,5-cyclodecadiene (6.76%), squalene (4.48%), stigmasterol (4.08%), γ-sitosterol (10.20%), Serratol (23.12%), vitamin E (2.78%) and lup-20(29)-en-3-one (21.04%). Based on a literature study, the presence of phytol, neophytadiene, β-caryophyllene, stigmasterol, γ-sitosterol, and lup-20(29)-en-3-one have contributed to the strong α-glucosidase inhibitory activity of n-Hexane extract of Merremia vitifolia leaves.

Penelitian ini bertujuan untuk mengetahui pengaruh impregnasi kaolin Pulau Bangka terhadap serapan terhadap ekstrak bunga kiacret dengan pelarut n-heksana. Impregnasi kaolin-ekstrak bunga kiacret dengan pelarut n-heksana ianalisis menggunakan FTIR dan Spektrofotometri UV-Vis. Berdasarkan analisis FTIR terjadi pergeseran bilangan gelombang pada 780 cm-1 ke 718 cm-1. Selain itu adanya pergeseran bilangan gelombang ekstrak bunga kiacret dari 1063 cm-1 ke 1044 cm-1 pada ekstrak bunga-kaolin teraktivasi. Spektra UV-Vis menunjukkan bahwa penambahan kaolin (variasi 2 gram) menyebabkan daerah serapan ekstrak kiacret n-heksana mengalami pelebaran hingga 404 cm.

TiO2-CaO and TiO2-CaO-Fe2O3 photocatalysts have been synthesized through the surfactant-assisted sol-gel method. The catalysts were characterized using XRD, FTIR, SEM-ED Sand BET surface area. XRD pattern showed the formation of anatase TiO2 crystal phase both in TiO2-CaO and TiO2-CaO-Fe2O3. The TiO2-CaO has higher crystallinity than TiO2-CaO-Fe2O3. Based on the peak refinement using Rietveld, there are two peaks identified as Fe2O3 hematite in the sample TiO2-CaO-Fe2O3.  BET surface area analysis showed that the average pore size of TiO2-CaO and TiO2-CaO-Fe2O3 catalysts are 8.04 and 8.41 nm respectively, indicating both catalysts are mesoporous.FTIR spectra show that the vibration of Ti-O, Ca-O, and Ca-TiO2 were observed in both catalysts. SEM images confirm that both catalysts are porous material. The catechol removal using TiO2-CaO and TiO2-CaO-Fe2O3 improved with the increase of catalyst concentration. After 360 minutes of UV radiation, the removal of catechol using TiO2-CaO-Fe2O3 reached 46.0%, 48.3%, and 69.2%, while when using TiO2-CaO, it reached 22.1%, 36.8%, and 57.0% for 0.1 g, 0.15 g, and 0.2 g of catalysts, respectively. The photocatalytic activity of TiO2-CaO-Fe2O3 is not so strong compared to TiO2-CaO catalyst but the catechol adsorption property of TiO2-CaO-Fe2O3 is higher than that of TiO2-CaO catalyst.

<p class="E-JournalAbstractBodyIndo">Melihat kondisi anak-anak di wilayah Pos Dumpit dimana ada anak yang tidak dapat bersekolah, dan ditemukan juga kondisi anak-anak yang seharusnya sudah berada di level yang tinggi akan tetapi secara kemampuan masih berada di level yang rendah. Hal ini disebabkan karena keterbatasan perekonomian keluarga dimana mata pencaharian keluarga itu sebagian besar buruh serabutan, kuli cuci piring, dan pemulung. Hal inilah yang menyebabkan kondisi pendidikan mereka kurang layak dibandingkan dengan anak-anak yang memperoleh pendidikan di tempat lain. Untuk itu bimbingan belajar Pos Dumpit hadir dan bertujuan untuk (1) Meningkatkan kemampuan membaca, menulis, dan menghitung pada anak-anak dengan cara memberikan pembelajaran yang menarik dan menyenangkan pada anak TK dan SD, (2) Membantu anak-anak dalam memahami pelajaran yang sulit di sekolah, (3) Membantu anak-anak dalam menanamkan sikap berjuang melalui belajar yang giat, (4) Membantu anak-anak dalam meningkatkan kemampuan berpikir dan perubahan tingkah laku pada anak-anak menuju ke arah yang lebih baik. Bimbingan belajar ini menghadirkan tutor-tutor yang sudah diperlengkapi secara pedagogy maupun ilmu pengetahuan. Strategi pembelajaran yang dipergunakan tutor bervariasi, disesuaikan dengan kebutuhan dari tutee dan tingkatan. Dengan melihat kebutuhan tutee, maka tutor dapat meningkatkan motivasi dan keinginan belajar mereka. Harapannya bimbingan belajar ini tetap dapat bermanfaat bagi anak-anak, masyarakat, dan menjadi pembelajaran juga untuk tutor.</p><p> </p><p>Kata kunci: Dumpit, bimbingan belajar, tutor</p>

There are two species of plant that grow flourishing all around Indonesia including in Banten and West Java which are Merremia vitifolia and Bidens pilosa. In this study we evaluate how these plants could be potentially used as natural preserver of fish product especially Auxis thazard, to inhibit the histamine formation, and to find out how this activity correlates to the substances in polar extract of B. pilosa flowers and M. vitifolia leaves. Liquid chromatography with tandem mass spectrometry (LC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) were used to identify the substances of the plant’s part extracts. There are 27 chemicals in M. vitifolia extract and 14 chemicals in B. pilosa extract that have been detected. A triglyceride has been detected, isolated, and characterized by FTIR, 1H-NMR and 13C-NMR from n-hexane extract of M. vitifolia supported by LC-MS/MS data. Histamine formation in fish was determined after 30 min treatment with 4-hydroxybenzoic acid solution is around 40 – 51 mg / 100 g of fish, while treatment with M. vitifolia and Bidens pilosa extracts were less than 10 mg / 100 g of fish. This is the indication of high potential of both extract as preserver of fish products. Many of the identified substances have bioactivity like antimicrobial, anticancer, anti-inflammatory, antioxidant, and more, which influence the extracts’ ability to inhibit the formation of histamine in fish.