by 6% and the odds ratio of myocardial infarc tion (MI) by 7%. 5 Muscle strength seems to be a significant determinant of the blood pressure (BP) response to isometric stress. 6 Blood pres sure is an essential component of arterial load (AL), which modulates cardiac output. Hemo dynamic load on the left ventricle may contrib ute to a higher risk of cardiac events, particular ly in patients with structural heart disease. 7 Our study aimed to obtain mechanistic insight into the possible association between muscle strength and AL. We investigated the correlation between grip and aortic characteristic impedance (Z ao ), INTRODUCTIONThe grip strength test serves as a tool that predicts muscular strength as well as endurance. It is also a prognostic marker asso ciated with diabetes, cardiovascular events and mortality. 1-3 A recent patient data pooled meta analysis showed that in patients with cardiac disorders, grip strength predicted cardiac death, all cause death, and hospitalization due to heart failure. 4 A Mendelian randomization study in vestigating the causal relationship between grip and health outcomes demonstrated that a 1 kg increase in genetically determined grip strength reduced the odds ratio of coronary artery disease

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