Aim: To evaluate the persistence and adherence of subcutaneous biologics in patients with psoriatic arthritis (PsA). Patients & methods: Psoriatic arthritis patients who initiated adalimumab, certolizumab pegol, etanercept, golimumab or secukinumab between 15 January 2016 and 31 July 2017 were identified in the Truven Databases. Outcomes included discontinuation rate, persistence and adherence over 12 months. Results: Of 1558 patients included, the 12-month discontinuation rate was lowest with secukinumab (36.5%), followed by adalimumab, golimumab, etanercept and certolizumab pegol (42.6–51.6%). Mean persistence ranged from 240.7 (certolizumab pegol) to 282.8 days (secukinumab). The mean proportion of days covered was highest with secukinumab (0.67) and lowest with certolizumab pegol (0.49). Conclusion: Patients who initiated secukinumab had the lowest discontinuation rate and highest persistence and adherence over 12 months.

This article explores the relationship between conflict, education and the intergenerational transmission of poverty in Northern Uganda using a Q-squared approach, which combines and sequences qualitative and quantitative approaches. The focus is on whether people with education have greater resilience than those without during and following periods of conflict and insecurity. Findings include that conflict in Northern Uganda has resulted in chronic and intergenerational poverty, and that education supports resilience during and following periods of conflict and insecurity – it is a ‘portable’ asset of great value. The article concludes that education should be supported by governments and donors during and post‐conflict. This will support resilience during conflict, limiting the poverty impact of conflict on households and enabling a speedier post‐conflict recovery. Copyright (C) 2010 John Wiley & Sons, Ltd.conflict , resilience , education , chronic poverty , intergenerational transmission of poverty , Uganda ,

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