The effects of pomegranate extract (PE) supplementation were evaluated on high-intensity exercise performance, blood flow, vessel diameter, oxygen saturation (SPO2), heart rate (HR), and blood pressure (BP). In a randomized, crossover design, nineteen recreationally resistance trained participants were randomly assigned to PE (1000 mg) or placebo (PL), which were consumed 30 min prior to a repeated sprint ability (RSA) test and repetitions to fatigue (RTF) on bench and leg press. The RSA consisted of ten six-second sprints on a friction-loaded cycle ergometer with 30 s recovery. Brachial artery blood flow and vessel diameter were assessed by ultrasound. Blood flow, vessel diameter, SPO2, HR, and BP were assessed at baseline, 30 min post ingestion, immediately post exercise (IPost), and 30 min post exercise (30minPost). With PE, blood flow significantly increased IPost RSA (mean difference [MD]=18.49 mL·min−1; P<0.05), and IPost and 30minPost RTF (P <0.05) according to confidence intervals (CI). Vessel diameter increased significantly 30minPost RSA according to CI and resulted in a significant interaction IPost and 30minPost RTF (P <0.05). With PE, according to CI, average and peak power output increased significantly in sprint 5 of the RSA (P <0.05). There was no significant difference between PE and PL for bench (P =0.25) or leg press (P =0.15) repetitions. Acute PE supplementation enhanced vessel diameter and blood flow, suggesting possible exercise performance enhancement from increased delivery of substrates and oxygen. The acute timing and capsule form of PE may be advantageous to athletic populations due to ergogenic effects, taste, and convenience.

Nutritional status is a strong predictor of postoperative outcomes and is recognized as an important component of surgical recovery programs. Adequate nutritional consumption is essential for addressing the surgical stress response and mitigating the loss of muscle mass, strength, and functionality. Especially in older patients, inadequate protein can lead to significant muscle atrophy, leading to a loss of independence and increased mortality risk. Current nutritional recommendations for surgery primarily focus on screening and prevention of malnutrition, pre-surgical fasting protocols, and combating post-surgical insulin resistance, while recommendations regarding macronutrient composition and timing around surgery are less established. The goal of this review is to highlight oral nutrition strategies that can be implemented leading up to and following major surgery to minimize atrophy and the resultant loss of functionality. The role of carbohydrate and especially protein/essential amino acids in combating the surgical stress cascade and supporting recovery are discussed. Practical considerations for nutrient timing to maximize oral nutritional intake, especially during the immediate pre- and post- surgical periods, are also be discussed.

Background Body volume (BV), one component of a four-compartment (4C) body composition model, is commonly assessed using air displacement plethysmography (BodPod). However, dual-energy x-ray absorptiometry (DEXA) has been proposed as an alternative method for calculating BV. Aims This investigation evalauted the validity and reliability of DEXA-derived BV measurement and a DEXA-derived 4C model (DEXA-4C) for percent body fat (%BF), fat mass (FM), and lean mass (LM). Methods A total sample of 127 men and women (Mean ± SD; Age: 35.8 ± 9.4 years; Body Mass: 98.1 ± 20.9 kg; Height: 176.3 ± 9.2 cm) completed a traditional 4C body composition reference assessment. A DEXA-4C model was created by linearly regressing BodPod BV with DEXA FM, LM, and bone mineral content as independent factors. The DEXA-4C model was validated in a random sub-sample of 27 subjects. Reliability was evaluated in a sample of 40 subjects that underwent a second session of identical testing. Results When BV derived from DEXA was applied to a 4C model, there were no significant differences in %BF (p=0.404), FM (p=0.295), or LM (p=0.295) when compared to the traditional 4C model. The approach was also reliable; BV was not different between trials (p=0.170). For BV, %BF, FM, and LM relative consistency values ranged from 0.995-0.998. Standard error of measurement for BV was 0.62L, ranging from 0.831-0.960kg. There were no significant differences between visits for %BF (p=0.075), FM (p=0.275), or LM (p=0.542). Conclusion The DEXA-4C model appears to be a valid and reliable method of estimating %BF, FM, and LM. The prediction of BV from DEXA simplifies the acquisition of 4C body composition by eliminating the need for an additional BV assessment.

The purpose of the current study was to evaluate changes in body composition, metabolic rate, and hormones during postcompetition recovery. Data were collected from natural physique athletes (7 male/8 female) within one week before (T1) competition, within one week after (T2), and 4-6 weeks after (T3) competition. Measures included body composition (fat mass [FM] and lean mass [LM] from ultrasongraphy), resting metabolic rate (RMR; indirect calorimetry), and salivary leptin, testosterone, cortisol, ghrelin, and insulin. Total body water (TBW; bioelectrical impedance spectroscopy) was measured at T1 and T2 in a subsample (n = 8) of athletes. Significant (p < .05) changes were observed for weight (T1 = 65.4 ± 12.2 kg, T2 = 67.4 ± 12.6, T3 = 69.3 ± 13.4; T3 > T2 > T1), LM (T1 = 57.6 ± 13.9 kg, T2 = 59.4 ± 14.2, T3 = 59.3 ± 14.2; T2 and T3 > T1), and FM (T1 = 7.7 ± 4.4 kg, T2 = 8.0 ± 4.4, T3 = 10.0 ± 6.2; T3 > T1 and T2). TBW increased from T1 to T2 (Δ=1.9 ± 1.3 L, p < .01). RMR increased from baseline (1612 ± 266 kcal/day; 92.0% of predicted) to T2 (1881 ± 329, 105.3%; p < .01) and T3 (1778 ± 257, 99.6%; p < .001). Cortisol was higher (p < .05) at T2 (0.41 ± 0.31 μg/dL) than T1 (0.34 ± 0.31) and T3 (0.35 ± 0.27). Male testosterone at T3 (186.6 ± 41.3 pg/mL) was greater than T2 (148.0 ± 44.6, p = .04). RMR changes were associated (p ≤ .05) with change in body fat percent (ΔBF%; r = .59) and T3 protein intake (r= .60); male testosterone changes were inversely associated (p≤ .05) with ΔBF%, ΔFM, and Δweight (r=-0.81--0.88). TBW increased within days of competition. Precompetition RMR suppression appeared to be variable and markedly reversed by overfeeding, and reverted toward normal levels following competition. RMR and male testosterone increased while FM was preferentially gained 4-6 weeks postcompetition.