Colonoscopy is regularly used for investigation of bowel pathology and has become the gold standard for screening and diagnosis of colorectal cancer (CRC). [1] The procedure has diagnostic and therapeutic benefits, such as direct visualisation of the entire colon and removal of precancerous polyps, which is associated with a lowered risk of CRC. [2] Colonoscopy is a skill-intensive procedure and poses a risk to the patient, even if performed by a trained endoscopist in an appropriate setting. [1] Therefore, there is a need for standardised practice and regular audit of endoscopists to ensure consistent, high-quality care. [3] Based on the 'adenoma-carcinoma sequence' hypothesis for developing CRC, screening and surveillance colonoscopy aim to detect and remove polyps, particularly adenomatous polyps, with the intention of reducing the incidence of CRC. [4] Therefore, the polyp detection rate (PDR) and adenoma detection rate (ADR) are two key indicators of the quality of endoscopy. Other measurable This open-access article is distributed under Creative Commons licence CC-BY-NC 4.0.
This case series confirms that FMT is a safe and effective therapy for recurrent CDAD. In most cases it can be administered via the nasogastric route in the outpatient department. We propose that the recently published South African Gastroenterology Society guidelines be reviewed with regard to recommendations for the route of administration of FMT and hospital admission. Meticulous prescription practice by clinicians practising in hospitals and outpatient settings, with particular attention to antimicrobials and chronic medication, is urgently required to prevent this debilitating and potentially life-threatening condition.
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