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Cyclohexanol (CHOL), as a value-added chemical, has attracted much attention due to its huge application market. The hydrogenation of cyclohexyl acetate (CHA), derived from the esterification of acetic acid and...

PTFE-filled textured surfaces were impregnated with the dopamine dipping solution to improve their tribological performances. Ball-on-disc wear experiments were conducted to compare tribological properties of three surfaces: the textured surface, filled textured surface and modified filled textured surface. The worn surfaces, wear debris, and shedding areas of the PTFE were measured, and shear strength between the PTFE block and medium carbon steel after impregnation modification was analysed. Experimental results showed that compared with textured surfaces, filled textured surfaces and modified filled textured surfaces had lower friction coefficient values and cross-sectional areas of wear scars. Compared with the filled textured surface, the modified filled textured surface reduces filled gaps by 63.5% and the shedding ratio of the PTFE within dimples by 63.2%. The research results demonstrate that tribological performances of the filled textured surface can improve after impregnation modification. Polydopamine can react to covalent-noncovalent interaction with PTFE and medium carbon steel. Polydopamine acts as a binder to improve the bonding strength between the PTFE and the inner wall of dimples. Polydopamine can reduce the shedding ratio of the PTFE and maintain the antifriction function of the PTFE in dimples.

Nitric oxide synthase- (NOS-) dependent endothelial dysfunction induced by oxidative stress (OS) is assumed to play a pivotal role in the pathogenesis and progression of diabetes mellitus-related erectile dysfunction (DMED). Cysteine-rich whey protein isolate (CR-WPI) is a widely used protein supplement and has been confirmed to reduce reactive oxygen species (ROS) by increasing cellular antioxidant glutathione (GSH). However, it is currently unknown whether CR-WPI elicits therapeutic effects in DMED. Here, we provide diabetic rats with CR-WPI to determine its effect on DMED and the underlying mechanisms. The results suggest that CR-WPI supplementation increased GSH biosynthesis and reduced ROS content and simultaneously upregulated the dimethylarginine dimethylaminohydrolase (DDAH)/asymmetrical dimethylarginine (ADMA)/nitric oxide synthase (NOS) metabolic pathway. Evaluation of intracavernous pressure (ICP) also showed an improvement of penile erectile function in CR-WPI-treated rats. The results of the vitro cell culture showed that glutathione pretreatment protected corpus cavernosum smooth muscle cells (CCSMC) from H2O2-induced apoptosis by decreasing Caspase 9 and Caspase 3 expressions. These results augur well for the potential therapeutic application of dietary CR-WPI supplementation for treating diabetic erectile dysfunction.