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Memantine is a low-affinity, voltage-dependent, non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist. It is classified as a neuroprotective aminoadamantane. It does not cure or reverse Alzheimer's but it does effectively treat symptoms, slows the progression of the disease and allows many patients to perform daily cognitive activities with clear thoughts. Based on it's success in patients with Alzheimer's, memantine has been tested in other neurological disorders with impaired learning and memory. In this review, we will discuss the success and failures of memantine in Downs Syndrome and Fragile X research and from those results, assess the potential benefit of memantine in Rett Syndrome (RTT).

This paper reports on a collaborative digital arts project conducted with LGBT youth and seniors in Vancouver, British Columbia, Canada, funded by the B.C. Council to Reduce Elder Abuse and conducted by faculty members and a doctoral student from Simon Fraser University. In the project, youth and seniors worked together to produce the first Canadian materials on LGBT elder abuse-three digital videos and five informational posters. We report on the methods used to produce and disseminate the materials, and as we reflect on the project's outcomes, we consider both the challenges and potential of digital literacies in this context.

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