Aims: For many centuries before the invention of conventional drugs plants were the drugs used for the treatment of many illness, till now it has been proven by a lot of researchers that many persons still prefer the use of herbal drugs including pregnant women. This study was carried to find out the plants used for management of pregnancy-related illnesses. Study Design: This was a cross-sectional study Place and Duration of Study: The study was carried out between January and May, 2019 within five local government areas of Edo State, Nigeria, which make up Benin City. Methodology: Ethnobotanical data were gathered through general conversations with informants in the field. Fifty people were interviewed during the course of the research. An oral interview was used to gather information, which was led by a semi-structured open-ended questionnaire within five local governments in Edo State. Results: Respondednts identified sixteen plants for management of pregnancy-related ailments. These sixteen plants' leaves, stems, and roots were primarily used. In the Amaryllidaiea family, Allium sativum, fruits and bulbs were used, whereas in the Euphorbiaceae family, Phyllantus amarus, all plant components were utilised. The Oredo local government had the highest percentage of responders who use Alchornia cordifolia from the Euphorbiaceae family for the treatment of pregnancy-related disorders, with 80 percent agreeing to use the plant. Conclusion: Among the 16 plants identified, the most-used were Jatropha curcas, Alchornea cordifolia, and Secamone afzelii.
Prostate Cancer has assumed an important public health concern in Nigeria. Its incidence is anecdotally on the rise in our community and many prominent Nigerians are dying from it. The current study set out to ascertain the age adjusted prostate specific antigen (PSA) values indigenous to the local community and to confirm the relationship between PSA and age. In this study, enrollees were from a medical outreach carried out by a non-governmental agency in Benin City, Nigeria. The number of volunteers was 443 adult males. Eleven 11(2.48%) of this number were excluded from the study on account of their outlying PSA values. The mean age was 42.4years; the youngest volunteer being 18 years and the oldest, 86 years. The mean PSA value in the ≤40 year, 40-49, 50-59, 60-69, and ≥70year age categories were 1.77 ng/ml, 2.09 ng/ml, 1.99 ng/ml, 2.63 ng/ml, and 2.59 ng/ml respectively. The overall mean PSA was 2.21 ng/ml, whereas the median was 2.09ng/ml. Results showed positive but weak correlation between age and PSA (R = 0.161, P < 0.01). Nonetheless, significant increases in PSA with age were reported. The current study therefore provides a set of serum PSA values that are indigenous to the local environment, which could be used as cutoff threshold for performing prostatic biopsies.
Aim:The aim of this study was to compare the serum magnesium levels of patients with breast cancer and apparently healthy people without the disease. Study Design: This is a cross-sectional prospective study.
Context: Preeclampsia is a multisystem disorder, although the cause is unknown, yet oxidative stress is a prominent feature; therefore, assessment of oxidative stress indices in preeclamptics would no doubt improve their clinical outcome. Aim: The aim of this study was to determine the antioxidant and malondialdehyde (MDA) status in preeclampsia. Setting and Design: This was a cross-sectional descriptive study. Subjects and Methods: One hundred and ninety-six (196) respondents consisting of 124 preeclampsia (PE), 36 normotensive pregnant women (NPW), and 36 analbuminuric hypertensive pregnant women (AHPW) participated in this study. Blood samples were collected for estimation of plasma uric acid, serum MDA, nitric oxide (NO), superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase (GSSH) and catalase (CAT) activities, Vitamin C (Vit C), and Vitamin E (Vit E) using standard methods. Statistical Analysis Used: The Statistical Package for the Social Sciences version 16 with level of significance set at P < 0.05 was used for statistical analysis. Results: Plasma uric acid level was significantly higher (P < 0.05) in PE than in AHPW and NPW. MDA levels, SOD, CAT, and GPX activities showed a significant increase (P < 0.05) in PE and AHPW when compared to NPW, while GSSH, NO, Vit C, and Vit E levels were significantly higher (P < 0.05) in NPW than in PE and AHPW. Most oxidative stress indicators were higher in PE and AHPW than in NPW in the 2nd and 3rd trimesters, while Vit C and E were lower. Plasma uric acid, MDA and NO levels, SOD, and GPX activities were significantly higher (P < 0.05) in severe than in mild PE. Conclusion: from our findings, it can be safely suggested that oxidative stress is related to the severity of preeclampsia.
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