The complex interaction of genetic and environmental influences in Huntington's disease results in successive generations living in deteriorating social circumstances. As the disease is untreatable (other than by palliative measures), spouses and unaffected children also suffer indirectly from its socio-psychiatric consequences.

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Three new cases of the syndrome of Capgras are presented. An unusual variant of the syndrome is recorded. It is contended that the definition of the syndrome should be widened to include impersonators who exhibit slight differences from the prototype, and that ambivalence and projection cannot explain all cases. The syndrome is critically reviewed.

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