Reports from popular medicine usually act as a basis for the development of new drugs from natural compounds with therapeutic actions for serious diseases and prevalence such as cancer. Bromelia antiacantha Bertol. is a species of the Bromeliaceae family, considered an unconventional food plant, found in the south and midwest regions of Brazil. Despite the high nutritional content and pharmacological potential of its fruits, few scientific studies report its biological actions. Thus, this study evaluates the phytochemical profile of aqueous and ethanol extracts obtained from B. antiacantha fruits, as well as their possible antioxidant, antitumor, and cytotoxic activities. The aqueous extract exhibited phenolic compounds and flavonoids, while ethanol extracts indicated the presence of flavonoids and coumarin in their composition, regardless of the region of collection. The ethanolic extract demonstrated a more promising antioxidant effect than the aqueous extract and also induced a significant inhibition in the viability of human cervical cancer cells of the SiHa strain. In addition, treatment with both extracts did not alter the viability of non-tumor cells of the immortalized human keratinocyte lineage (HaCaT). These results bring new data about extracts obtained from a native plant, edible and traditionally used in popular medicine, opening new perspectives for its possible therapeutic application.
Objetivou-se avaliar a utilização de bagaço de mandioca (BM) em rações suplementadas com complexo enzimático (CE) para frangos de corte em duas fases. Foram avaliados o ganho de peso (GP), consumo de ração (CR) e conversão alimentar (CA) de frangos de corte nas fases de 1 a 21 e 22 a 40 dias, alimentados com rações contendo 0 e 20 % de inclusão de BM com e sem adição de CE. Os experimentos foram realizados num delineamento experimental em blocos casualizados com 4 tratamentos utilizando um arranjo fatorial 2x2 (0 e 20 % de BM, com e sem CE) com 8 repetições e 20 aves por unidade experimental. Não foi observada interação entre os tratamentos, inclusão de BM e CE. A inclusão do BM diminuiu o CR e o GP em ambas as fases de criação. Enquanto que a inclusão do CE melhorou o GP e a CA das aves na fase inicial, não afetando o desempenho na fase de 22 a 40 dias de idade, já menor custo de ração por quilograma de ganho de peso e os melhores índices de eficiência econômica e de custo para ambas as fases foi encontrado para os animais que foram submetidos a rações com 0 % de inclusão de bagaço de mandioca com adição de complexo enzimático.
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