Nb3S n accelerator magnet technology has made s i gnificant progress during the past decades. For the first time, it is planned to be used in a real accelerator. A relatively small number of Nb3S n quadrupoles and dipoles will be installed in th e LHC to increase machine luminosity. Although it will prove the possibil ity of using Nb3S n magnets in real machines, many questions of s caling this technology up remain. One of them is related to slow training of Nb3S n magnets compared to the traditional Nb-Ti accele rator magnets. S ince the goal is to operate thousands of Nb3S n magnets in a future post-LHC accelerator, the slow training will affe ct both the practical design margin and the nominal operation fi eld. Consequently, the cost of the project to reach the design field le ve l is also increased. To improve our understanding of slow magnet training the existing Fermilab data from Nb3S n magnet tests we re re-analyzed. A summary of coil training features and correlation s with fabrication parameters observed is presented in this paper.
Our main objective was to validate that hyperspectral imaging via a new portable camera carries the potential to provide a reliable clinical biomarker that can predict DFU healing. We recruited patients with diabetic foot ulceration (DFU) without peripheral arterial disease, infection or other serious illness. Using an hyperspectral imaging (HSI) apparatus, post-debridement hyperspectral images were taken evaluating the ulcer size, periwound oxyhemoglobin (OxyHb), deoxyhemoglobin level (DeoxyHb) and oxygen saturation (O 2 Sat) for four consecutive visits. Twenty-seven patients were followed, out of whom seven healed their DFU while the remaining 20 failed to heal their DFU. The average time between each visit was 3 weeks. Binary logistic regression of healers versus non-healers on Visit 1 oxyHb and on Visit 2 showed a significant inverse association, OR = 0.85 (95% CI: 0.73-0.98, p < 0.001).An inverse correlation was observed between the Visit 1 oxyHb and the percentage of ulcer size reduction between Visit 1 and Visit 4 (r = À0.46, p = 0.02) and between the Visit 2 oxyHb and the percentage of ulcer size reduction between Visits 2 and 4 (r = À0.65, p = 0.001). Using oxyHb 50 as the cut-off point to predict DFU complete healing, Visit 1 oxyHb measurement provided 85% sensitivity, 70% specificity, 50% positive predictive value and 93% negative predictive value. For Visit 2, oxyHb had 85% sensitivity, 85% specificity, 66% positive predictive value and 94% negative predictive value. We conclude that this preliminary study, which involved a relatively small number of patients, indicates that hyperspectral imaging is a simple exam that can easily be added to daily clinical practice and has the potential to provide useful information regarding the healing potential of DFU over a short period of time.
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