Introduction: The increasing prevalence of depression and irregular dietary pattern amongst adolescent, especially women, has become an important issue today. A number of studies confirm that dietary pattern plays a role as one of the biological factors affecting mood regulation through the production of nerotransmitters, however, there are conflicting results regarding the matter in adolescent. This study aimed to examine the correlation between dietary pattern and depression in adolescent. Methods: This study was done through cross sectional analytical observational study in 89 high school students in SMAK St. Louis Surabaya. The data was gathered through two types of questionnaires filled by the respondents. The questionnaires were Food Frequency Questionnaire to assess dietary intake pattern and Beck Depression Inventory to assess the occurence of depression amongst the respondents. Results: The study showed high prevalence of irregular dietary pattern and depression within the sample. From Spearman correlation test, there is no correlation between dietary pattern and the prevalence as well as the degree of depression (p > 0,05). Conclusion: There is no correlation between dietary pattern and depression in adolescent. It may be caused by a lot of other factors contributing to the occurence of depression, including biological, psychological, and social factors.

Background: Ketogenic diet is a high lipid, low carbohydrate, and adequate protein diet. It has long been used as a therapy in refractory epilepsy patients, but very little is known about the long-term effects. Objectives: This study was conducted to analyze the effect of a ketogenic diet on carotid artery thickness and elasticity in patients with epilepsy. Discussion: Literature searches were conducted through search engines such as PubMed, ScienceDirect, and Google Scholar, resulting in four studies that were eligible for inclusion and have passed the selection process based on PRISMA flowchart and JBI critical appraisal. These studies involved patients with refractory epilepsy (13 months to 31 years old), who were given ketogenic diet therapy for at least 6 months. Carotid artery elasticity decreased significantly on the ketogenic diet given for 12 months (p<0.001). However, it was not accompanied by a significant change in wall thickness, which was assessed through carotid intima-media thickness (CIMT). Most studies found an increased cardiovascular risk due to an increase in lipid profile and carotid artery stiffness. Conclusions: In conclusion, the ketogenic diet affects the carotid artery elasticity without changing the thickness, also increases lipid levels reversibly, and is thought to increase cardiovascular risk in patients with refractory epilepsy.