Background: The fallopian tube functions as an anatomic and physiologic link between the ovary and the uterus in reproduction by ensuring efcient and orderly ovum transport and providing a proper environment in which fertilization occurs. Not much studies has been done about the lesions of fallopian tube and its relation to the lesions of uterus and ovaries Objectives: To study the various histopathological lesions of uterus, ovaries and fallopian tubes. To correlate the possible relation of the lesions in the uterus and the ovaries to the changes in the fallopian tubes. Materials And Methods: This study was carried out in the department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur, India . A total of 80(Eighty) specimens of total abdominal hysterectomy with bilateral salpingoophorectomy from patients who underwent surgery in the Obstetrics and Gynecology department of Regional Institute of Medical Sciences Hospital were obtained for study for a duration of 2 years starting from May 2015 to April 2017. Majority of cases were with a clinical Results: diagnosis of uterine broid followed by chronic cervicitis and DUB. The incidence of tubal lesion was 18.75% and tubes with normal ndings comprised 88.75%. It is well appreciated that the Conclusion conditions involving the fallopian tube are frequently non neoplastic pathologic conditions like ectopic pregnancy, acute and chronic salpingitis in contrast to the neoplastic conditions.

Background: Papulosquamous skin disorder is a group of heterogenous dermatoses with a distinct histomorphological feature. The characteristic primary lesion is a papule, usually erythematous, that has a variable amount of scaling on the surface. The most common papulosquamous dermatoses are psoriasis, lichen planus, and pityriasis rosea. Because all papulosquamous disorders are characterized by scaling papules, clinical confusion may result during their diagnosis. Our study is to evaluate histomorphological findings in various papulosquamous skin disorders encountered at RIMS, Imphal. Materials and Methods: Skin biopsies of clinically diagnosed papulosquamous skin disorders along with their relevant clinical data received during a period of 2 years from September 2017 to August 2019 were included in the study. The diagnosis was confirmed by histopathological examination using hematoxylin and eosin stain. Results: A total of 115 papulosquamous skin disorders were studied with 75 cases of psoriasis (11–80 years), 36 cases of lichen planus (2–70 years), and 4 cases of pityriasis rosea. Age ranges from 2 to 80 years. Maximum cases were seen in the age group of 31–50 (70.6%) with a mean age of 39.18 years. Both genders were almost equally affected with a male: female ratio of 1.13:1. An analysis of the clinical with histopathological diagnosis of these papulosquamous skin lesions revealed a positive correlation in 76 (66.08%) cases and a negative correlation in 39 (2.9%) cases. Conclusion: Because of the varied clinical presentation and histopathological patterns of papulosquamous skin disorder, it is important to characterize the types of papulosquamous lesions as far as possible for definitive treatment.

BACKGROUND: Nasopharyngeal carcinoma accounts for a fair number of malignancies in the head and neck region. Cancerous growth in this location maybe very small and inconspicuous. Frequent clinical examination and repeated biopsy needs to be taken to come to an early diagnosis. FNAC can be utilized as a reliable and quick tool to aid in the early diagnosis of nasopharyngeal carcinoma before the patient is subjected to biopsy. FNAC if followed by biopsy rules out any false negative cases by FNAC and further reduces the chances of missing out on a diagnosis of nasopharyngeal carcinoma. OBJECTIVES :To compare the role of FNAC and biopsy in the rapid diagnosis of nasopharyngeal carcinoma. MATERIALS AND METHODS: All suspected case of nasopharyngeal carcinoma underwent FNAC followed by biopsy . FNAC smears were stained with Giemsa stain and biopsy sections were stained in hematoxyline and eosin (H&E) .Special stains were used whenever indicated. RESULTS: Nasopharyngeal carcinoma affected males more than the females and most of the cases were in their 4th - 5th decade . There was a clear preponderance of nasopharyngeal carcinoma amongst the tribal community accounting for 69% of the cases. Metastatic lymph nodes in varied locations were found to be present in 60% of the cases studied. Success rate of FNAC in the rst half of the cases was 26.6% which increased to 60% in the second half of the cases. Biopsy revealed a success rate of 80 % and 66.6 % in the rst and second half of the cases respectively. Out of the 22 histopathologically conrmed cases of nasopharyngeal carcinoma, FNAC could correctly diagnose 63.3 % of the cases and there were no false positive cases. The overall diagnostic accuracy of FNAC was 68 % with a sensitivity of 46.7%, specicity of 100 % while predictive positive value was 100 % and predictive negative value was 55.5 % . CONCLUSION: FNAC is a safe, reliable , cost effective technique for the early diagnosis of nasopharyngeal carcinoma . Other diagnostic modalitieslike endoscopic FNAC or CT guided FNAC may also be incorporated to improve the detection rate in early and deep-seated cases of nasopharyngeal carcinoma.

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Background: Distinction between reactive mesothelial cells, malignant mesothelioma and carcinoma is challenging in both biopsy and cytologic material. This study was conducted to differentiate benign/ reactive mesothelial proliferation from malignant mesothelial proliferations and metastatic adenocarcinoma by using immunohistochemical (IHC) markers Desmin (DES), Epithelial membrane antigen (EMA) and Calretinin (CAL) in pleural uid cell block (CB) preparations. A two year descriptive study (Oct.2016- Sept.2018). 46 pleural uids samples sentMethods : to the Dept. of Pathology, RIMS for routine examination and histopathological examination by CB preparation were studied using IHC markers EMA,DES and CAL following H & E stain. Out of 46 cases, 9(19.6%) cases were diagnosed as benign, 23(50.0%) as reactive andResults: 14(30.4%) as adenocarcinoma on H & E section by CB preparations within an age range 34 to 80 years (Mean±SE, 60.32±12.13). Following IHC staining with EMA, DES & CAL, 11(23.9%) cases were conrmed as benign, 17(37.0%) as reactive, 16(34.8%) as adenocarcinoma and 2(4.3%) cases as malignant mesothelioma. This study showed that EMA, DES and CAL helpful in conrming benign or reactive mesothelialConclusions: and malignant mesothelial with epithelial cells which will be helpful in providing appropriate diagnosis in difcult cases and provide better patient management.