every 2 s for 24 s followed by 1 volume every 5 s for another 20 s with an acquisition delay of 7 s. The acquisition parameters were 80 KVand 100 mA with a rotation time of 1 s. The post-processing of all perfusion studies was on a Vitrea fx V.1.0 workstation (Vital Images Inc, Minnesota, Wisconsin, USA) using singular value decomposition plus deconvolution method. Cerebral blood flow, cerebral blood volume and mean transit time were calculated in the two cerebellar hemispheres and were compared using paired t test. A p value of less that 0.005 was taken as significant. Results: In all 11 patients, the relative regional cerebellar blood volume (p , 0.0001) and flow (p 5 0.0005) values of the non-affected cerebellar hemisphere were significantly larger than those of the affected side. Conclusion: The relative regional cerebellar blood volume map obtained with whole brain perfusion on 320-slice CT scanner depicted findings compatible with crossed cerebellar diaschisis in patients with supratentorial stroke. Its clinical feasibility may be further confirmed by direct comparison with PET or single photon emission computed tomography in a larger population.Objective: Dominance of arteries has been studied in different tissues/organs of body. Diagnostic, therapeutic and prognostic implications are hypothesized to be related to symmetry or asymmetry of circulation. One major implication in the case of the brain is the hypotheses that asymmetry exists due to differences in vascular requirements of the brain tissue. Vertebral artery origin and its dominance have not been properly studied, especially on CT angiography. Since neurovascular intervention is increasingly becoming common, this information will be helpful in determining suitable access to basilar artery. Decreased bending of the basilar artery has also been reported to be related to dominance of the vertebral artery. Methods: This retrospective analysis included only ischemic stroke patients that were admitted at Froedtert Medical Luther Hospital (FMLH) between September 2007 and May 2008. The CT angiographic image was read by blinded readers. All were given printed forms on which they marked: dominance, small, hypoplastic or codominant for each side. The data were then gathered and analyzed. Dominance was defined on the basis of comparative luminal diameter and degree of flow. Results: Of 134 patients assessed; we found that vertebral artery origin is co-dominant in 31.8% (n 5 27) of patients. The right side was dominant in 21.6% (n 5 29); small in 11.9% (n 5 16); and hypoplastic in 1.5% (n 5 2). The left side was dominant in 37.3% (n 5 50); small in 6.75% (n 5 9); and hypoplastic in 0.7% (n 5 1). Although intracranially the ratio is different and the left side is still more dominant (24.7%) than the right side (18.8%), co-dominance was much less (4.7%). Conclusion: Left side is most commonly found to be dominant in vertebral artery origin and co-dominance is the second most common form of dominance in vertebral arteries. Competing interests: None.98
Background: Rabies is only communicable disease of man that is always fatal but easily preventable disease, if animal bites are appropriately and timely managed. It is estimated that India continues to report every year 25,000 to 30,000 human rabies deaths. The objective of this study was to describe the clinic epidemiological characteristics of human rabies.Methods: Analysis of the records of probable rabies cases admitted into the Infectious Diseases Hospital, KGMU, Lucknow during 2010-2014.Results: Total 490 human rabies cases were admitted during study period. Majority (63.26%) of the victims were between 12-60 years of age. Males constituted 83.47% of cases and victims from rural areas were 92.65%. Principal biting animal was dog (94.29%). Majority of the cases (77.96%) were not vaccinated. Most of the cases (93.47%) left against medical advice within 24 hours after admission.Conclusions: Rabies is a major health problem in this part of India. The data indicates that there is still much to do for mitigation of this menace and the crux of the problem is the epidemiological trend has not changed much. Hence, there is an immediate and urgent need to educate the community and health workers about the importance of immediate and adequate post-exposure treatment. Prevention strategies are critical to better manage rabies in these endemic areas.
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