Reaction of 1-aryl-3-arylcarbonylthioureas with dialkyl acetylenedicarboxylates in CH(2)Cl(2) at room temperature leads to alkyl 2-[2-(arylcarbonylimino)-3-aryl-4-oxo-1,3-thiazolan-5-ylidene]-acetates in good yields.

naphthalen-1-yl}thiourea with dialkyl acetylenedicarboxylates in CH 2 Cl 2 leads to alkyl (2-(2lidin-5-ylidene)acetates in good yields.

in Wiley Online Library (wileyonlinelibrary.com).Reaction of 4-phenylthiosemicarbazide with dialkyl acetylenedicarboxylate in CH 2 Cl 2 at 0 C lead to construction of alkyl 3-amino-2-phenyliminothiazolidine-4-one-5-ylidene acetate in a few minutes and good yields. Alternatively, the use of thiosemicarbazide has given the corresponding 3-amino-2-iminothiazolidine-4-one-5-ylidene acetate, while application of di-t-butylacetylenedicarboxylate in these reactions has not entailed with cyclization.

No abstract

Thiazole derivatives R 0260 Efficient Synthesis of Alkyl 2-[2-(Arylcarbonylimino)-3-aryl-4-oxo-1,3-thia-zolan-5-ylidene]-acetates. -(YAVARI, I.; SABBAGHAN, M.; PORSHAMSIAN, K.; BAGHERI, M.; AL-ASGARI, S.; HOSSAINI, Z.; Mol. Diversity 11 (2007) 2, 81-85; Dep. Chem., Islamic Azad Univ., Ponak, Tehran, Iran; Eng.) -Bartels 14-147