Background: Atopic dermatitis is a chronic and residive skin inflammation, which is often found in patients with allergic rhinitis and asthma and among their family members, which is characterized by skin disorders in the form of itchy papules, which then undergo excoriation and lichenification, distribution in body folds. At the age of 4-16 years, the predilection for dermatitis is found on the upper body and face, generally symmetrical dermatitis appears in the flexure area, hands, and feet.Case Presentation: The following is a case report of a 16-year-old male patient as a student. The patient was diagnosed with atopic dermatitis with complaints of itching in the neck area, hand folds, and leg folds. Initially itchy, filled with clear fluid in the neck then spread to the folds of the hands and feet. Itchy, hot, and painful when sweating. Lesions ad Regio colli, superior and inferior extremities show lichenified lesions with irregular shape, poorly demarcated with bilateral spread, accompanied by squama and excoriations.Conclusion: Atopic dermatitis is a chronic inflammation of the skin, which may manifest as itchy papules that become excoriated and lichenified. Predilection can be determined based on the age of the patient.

Gagal jantung merupakan masalah kesehatan masyarakat dengan angka morbiditas dan mortalitas yang cukup besar, serta risiko kematian yang tinggi pada negara maju maupun negara berkembang, sehingga membutuhkan manajemen terapi yang tepat untuk mengurangi morbiditas dan mortalitas. Angiotensinconverting enzyme inhibitor (ACEI) atau angiotensin receptor blocker (ARB) adalah standar perawatan yang biasa digunakan selama ini, namun sacubtril/valsartan banyak dibicarakan dan memberikan resiko kematian yang lebih rendah serta mengurangi rehospitalisasi pada pasien gagal jantung dibandingkan dengan penggunaan ACEI. Oleh karena itu, sacubtril/valsartan cenderung lebih hemat biaya dibandingkan dengan ACEI (standar perawatan saat ini). Tujuan penulisan ini untuk mengetahui efektivitas biaya sacubtril/valsartan dibandingkan dengan enalapril (ACEI) dalam pengobatan gagal jantung dengan fraksi ejeksi berkurang.

COVID-19 (Coronavirus Disease 2019) is still a significant problem; therefore, mental health issues and COVID-19 are starting to get attention because of the increasing psychological impact and mainly because of Substance Use Disorder (SUD). Further study is required on this issue. This paper aimed to determine the prevalence, diagnosis, and treatment of SUD during the COVID-19 pandemic. This literature review is gained from scientific articles with a range of publication years from 2016 to 2021 about SUD During the COVID-19 pandemic based on Prevalence, Diagnosis, and psychotherapy of the published journal using Pubmed, Google Scholar, and SAGE Journals, and then critically reviewed. The prevalence of SUD patients during the COVID-19 pandemic has increased; however, digital psychotherapy strategies for SUD patients have been found and proved effective during the pandemic. In conclusion, the COVID-19 pandemic impacts a person's mental and behavior and could be a high-risk opportunity for substance abuse. Therefore health workers must improve health services for SUD patients to receive the health access needed even in a pandemic.Keywords: Mental Health, Substance Use Disorder, COVID-19, Prevalence, Diagnosis, ManagementCorrespondence : dedydermawan555@gmail.com