Herein, we report an operationally simple, ligand- and additive-free oxidative boron-Heck coupling that is compatible with the ethenesulfonyl fluoride functional group. The protocol proceeds at room temperature with chemoselectivity and E-isomer selectivity and offers facile access to a wide range of β-aryl/heteroaryl ethenesulfonyl fluorides from commercial boronic acids. Furthermore, we demonstrate a "one-pot click" reaction to directly transform the products to aryl-substituted β-sultams.

C34H39NOSi, triclinic, P1̅ (no. 2), a = 10.0901(2) Å, b = 11.5016(2) Å, c = 14.4098(3) Å, α = 69.207(1)°, β = 86.555(2)°, γ = 65.579(3)°, V = 1416.10(6) Å3, Z = 2, Rgt(F) = 0.0463, wRref(F2) = 0.1200, T = 100(2) K.

No abstract

C 9 H 13 FO5S, triclinic, CCDC no.: 1528194The crystal structure is shown in the figure. Crystal data, data collection and structure refinement details are summarized in Tables 1. Tables 2 lists the Source of materialA mixture of methyl 2-oxocyclopentane carboxylate (20 mg, 1.0 eq), thiourea (N,N-diisopropylethylamine; 0.20 eq) and DIPEA (0.20 eq) was stirred in toluene (1.0 mL) at room