Kjersti Fremmerlid scite author profile

Background: MyD88 directly interacts and affects IRF activation in mammals, but no information has been available about lower vertebrates. Results: Transgenic MyD88 interacts with IRF3 and IRF7A/B and modulates the IRF-induced IFN response and accumulates in aggresomes in Atlantic salmon. Conclusion: MyD88 is involved in the regulation of the IRF-induced IFN response in Atlantic salmon. Significance: The results shed light on the evolution of the innate immune response in vertebrates.

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Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar)

Johansen

Jørgensen

Thim

et al. 2013

Fish & Shellfish Immunology

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Kjersti Fremmerlid

Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in heart of Atlantic salmon (Salmo salar L)

MyD88 Interacts with Interferon Regulatory Factor (IRF) 3 and IRF7 in Atlantic Salmon (Salmo salar)

Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar)

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