Background: This study aimed to assess the prevalence and course of endometriosis in adolescents with obstructive Müllerian anomalies. Methods: The study group involved 50 adolescents undergoing surgeries (median age 13.5 (range 11.1–18.5)) for rare obstructive malformations of the genital tract: 15 girls had anomalies associated with cryptomenorrhea and 35 were menstruating. The median follow-up period was 2.4 (ranging from 0.1 to 9.5) years. Results: We diagnosed endometriosis in 23 of the 50 subjects (46%), including 10 of the 23 patients (43.5%) with obstructed hemivagina ipsilateral renal anomaly syndrome (OHVIRAS), six of eight patients (75%) with a unicornuate uterus with a non-communicating functional horn, two of three patients (66.7%) with distal vaginal aplasia, and five of five patients (100%) with cervicovaginal aplasia. Persistent dysmenorrhea, following treatment, affected 14 of the 50 adolescents (28%), including 8 of the 17 subjects (47.1%) diagnosed with endometriosis at the time of surgical correction and six adolescents diagnosed with endometriosis during the follow-up. Conclusions: Endometriosis affects about half of young adolescents undergoing surgical treatment of obstructive Müllerian anomalies after menarche. The incidence of endometriosis is highest in girls with cervical aplasia. The risk of developing endometriosis decreases after surgical correction of obstruction but is still significant in patients with uterine anomalies.

Objective: Although these days the priority is to fight the Covid-19 pandemic, the importance of human papillomavirus (HPV) infection is not to be neglected. Mechanism: Cervical cancer is caused mainly by a chronic infection with one or more of the high-risk subtypes of HPV -most commonly a sexually transmitted disease acquired early in life. Most HPV infections go away on their own, but some can lead to a precancerous state that, if left untreated, can undergo complete neoplastic transformation. Findings in Brief: There is a hope that in the future the combination of screening tests with vaccinations against oncogenic strains of HPV will allow reductions in the percentage of those contracting cervical cancer. Conclusions: The importance of educational activities should be emphasized in developmental gynecology in the context of oncological prevention. The roles of both doctors and nurses are important here. During the Covid-19 Pandemic, these kinds of activities are not to be abandoned. In addition, efforts should be made to develop more practical and workable HPV and cervical screening strategies for use during a pandemic.

Introduction. The Female Sexual Function Index (FSFI) is considered to be an excellent tool for assessing female sexuality and screening for sexual dysfunctions in women. Aim. An attempt was made to demonstrate the desirability of using the FSFI questionnaire in gynaecological and general practice. Materials and methods. The study included 147 mature women (18 to 63 years of age) who reported for preventive gynaecological examinations and agreed to answer questions about their sexuality in the form of an anonymous FSFI questionnaire. Before proceeding with the questionnaire, the patients were asked, as part of an expanded medical history, if they received sexual education in their subjective assessment. Results. The average FSFI scores for all domains and the FSFI total score were higher in women with basic sex education compared to women who received no such education. Conclusions. Regardless of the issue of sex education, the important aspect of gynaecological counselling is the sexological aspect – it is also important in the general practice. This sphere still seems to be a taboo subject in many patients. The usefulness of the IFSK questionnaire for assessing female sexuality and the factors influencing it was confirmed.

<b><i>Introduction:</i></b> The objective of this study was to elucidate the efficacy of long-term amnioinfusion on perinatal outcomes in patients with preterm premature rupture of membranes (PPROM) before 26 weeks’ gestation. <b><i>Material:</i></b> A total of 31 patients with PPROM at a periviable gestational age (21 + 0–25 + 0 weeks) were enrolled. Long-term amnioinfusion was performed in 22 patients, and 9 patients did not receive amnioinfusion. Data were collected retrospectively from 2 clinical sites between January 2017 and March 2019. <b><i>Results:</i></b> In the medical management group, there was a significantly higher rate of chorioamnionitis compared to the long-term amnioinfusion group (89 vs. 15%, <i>p</i> = 0.001). The latency period between PPROM and delivery was higher in the amnioinfusion group (median, 5.5 vs. 3 weeks, <i>p</i> = 0.04). The frequency of bronchopulmonary dysplasia was higher in the control group compared to the amnioinfusion group (89 vs. 40%, <i>p</i> = 0.03). The rates of other neonatal complications were similar in both groups. <b><i>Conclusions:</i></b> Long-term amnioinfusion through an intrauterine catheter in PPROM before 26 weeks’ gestation may improve pregnancy and newborn outcomes.

Selected aspects related to the holistic approach to the problem of pain and suffering in GP practice are presented. Medicine is a limitless source for philosophical reflections – the issue of suffering and pain has always appeared here. COVID-19 is a new, highly contagious disease that causes modern men’s suffering. The forms of the disease and treatment methods are briefly described. Reflections of the contemporary world together with the unpleasant experience of the SARS-CoV-2 pandemic prompts humanistic searches. The experience of medicine, including family medicine, also in the very modern context of the coronavirus pandemic, shows that focusing on family physician practice only on the sphere of somatosis is absolutely insufficient.