The frequency of occurrence, trigger factors, supporting mechanisms of arrhythmia and paroxysmal supra-ventricular tachyarrhythmias in non-pregnant and pregnant women were studied. The study involved 26 non-pregnant women aged 18 to 29 years (25,8+2.2 years) and 30 pregnant women from 20 to 32 years (25,6+2,8) without complaint and without structural heart disease. Holter monitoring of ECG and transesophageal electrophysiological study of the heart were performed in all patients. It is revealed that there are arrythmia and paroxysmal supra-ventricular tachycardia in pregnant women more often than in non-pregnant. Reducing the number of extrasystoles and paroxysmal supra-ventricular tachyarrhythmias occurs 6 months after birth. It is established that in non-pregnant and pregnant women there are four types of curves atrio-ventricular conduction (AVC): continuous, intermittent, continuous with the phenomenon of the "gap", intermittent with the phenomenon of the "gap". The continuous curve type of AVC is detected in non-pregnant women, in pregnant women – intermittent, in women six months after childbirth - continuous. It is proved that the electrophysiologi-cal substrate curves atrio-ventricular conduction is retrograde functioning additional channel and longitudinal dissociation of atrio-ventricular connections on the fast and slow ways.
Tests of the antiparasitic agent Albicomum 10% VK were carried out in the Uvinsky and Zavyalovsky districts of the Udmurt Republic on animals spontaneously infested by the association of helminthiases. Animals of the first group were infested with fasciolous-strongylatosis invasion, the second - with mixed invasion of dicroceliosis + gastrointestinal strongylatosis, cows spontaneously infested with three types of helminths (fascioliasis + dicroceliosis + gastrointestinal strongylatosis) were in the third experimental group. Control groups were also formed with the corresponding associations of parasites, in which the intensity and extensity of infestation remained at a high level throughout the entire experiment. In the first (fascioliasis + gastrointestinal strongilatoses) and in the second (dicroceliosis + gastrointestinal strongylatoses) groups, all treated animals were completely freed from helminths on the 45th day. The extensibility of the drug was 100%. On the 90th day after the treatment, the effectiveness of the drug decreased by 10%. In case of fasciolous- dicrocelious-strongylatous association, the drug showed low efficiency.
In 1 g of feces of the treated animals, an average of 9.7 eggs of trematodes were found. In production trials, Albicomum 10% VK showed the highest efficiency (90%) in two-component helminthoses.
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