Syzygium cumini (L.) Skeels, commonly known as Jamun, is a widely distributed forest tree in India and other tropical and sub tropical regions of the world. The tree has a great economic importance since most of the parts like the bark, leaves, seed and fruits are used as an alternative medicine to treat various diseases. The present study aimed at the in-vitro anthelmintic activity of aqueous fruit seed extract of Syzygium cumini. The fruit seeds were extracted separately with distilled water by maceration method .The various concentrations of the extract (50,100, 200,300,400mg/ml) respectively were screened for their anthelmintic activity using Pheritima posthuma. The activity was comparable with the standard drug albendazole. When the concentrations of the extract are increased, a gradual increase in anthelmintic activity is observed. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. Aqueous fruit seed extract of Syzygium cumini showed anthelmintic activity against Indian earthworms. The data were found statistically significant by using one way ANOVA (P< 0.001).

The present study was to evaluate the phytochemical screening and anthelmintic activity of aqueous polyherbal seed extract (APSE) against Pheretima posthuma. The seeds of Helianthus annuus, Cucurbita pepo, Linum usitatissimum, Citrullus lanatus and Cucumis melo was identified and purchased from local market of Nuzvid. APSE was prepared from the dried seeds of five different seeds using the solvent water. Initially, APSE was screened for phytochemical constituents by standard methods. Further, anthelmintic study was conducted against Pheretima posthuma, collected from local Vermicomposting Farm, Nuzvid. In the phytochemical screening, APSE showed presence of glycosides, alkaloids, flavonoids, phenols, phytosterols and tannins. In the anthelmintic study, mortality was produced in earth worm populations by APSE. The use of APSE as an anthelmintic was confirmed by using standard method against Pheretima posthuma. The results indicated that the test drug has significant anthelmintic properties. Hence, it can be concluded that the APSE can be used as a novel drug for the treatment of worm infestations.

Syzygium cumini and Achras zapota leaves were easily available and commonly used in our day –to-day life. The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous extracts of leaves of Syzygium cumini, Achras zapota and mixed. The fruits were extracted separately with distilled water by maceration method .The various concentrations of the extract (50,100, 200mg/ml) respectively were screened for their anthelmintic activity using Pheritima posthuma. The activity was comparable with the standard drug albendazole. When the concentrations of the extract are increased, a gradual increase in anthelmintic activity is observed. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. Aqueous extract of Syzygium cumini, Achras zapota and mixed showed anthelmintic activity but mixed extract was more efficient anthelmintic activity against Indian earthworms. The data were found statistically significant by using one way ANOVA (P< 0.0001).