The purpose of the study is to clarify the essence and outline the functions of the international convention-institutional mechanism for the observance and protection of human rights, as well as to reveal the directions of its interaction with the national system of administrative and legal protection of the rights and freedoms of persons with disabilities of Ukraine. We use methods of scientific knowledge, in particular system-functional, formal-legal, technical-legal, methods of analysis and synthesis. The National system of ensuring the rights and freedoms of persons with disabilities of Ukraine, which is presented in the form of a three-level structure, among which: organizational level - is implemented by the Commissioner of the President of Ukraine for the Rights of Persons with Disabilities and the Government Commissioner for the Rights of Persons with Disabilities; management level – the Cabinet of Ministers of Ukraine; functional level – individual central bodies of the executive power of Ukraine, their structural units and local self-government bodies. The key directions and principles of coordinated interaction of public administration subjects with relevant international institutions, primarily the UN and the Council of Europe, in the analyzed area are indicated.

The article is devoted to the topical problem of ensuring the economic security of organizations. The subject of research is the economic security of the enterprise. The author substantiates the need to ensure the economic security of the organization for its stable and sustainable development. The essence of economic security of economic entities is revealed as such a state of protection of the subject from internal and external factors, in which he most effectively uses his potential, while reducing or eliminating existing risks or other circumstances to protect against them and achieve the main goal commercial activity in a competitive market. A set of measures aimed at studying the internal and external adverse economic factors and risks. Thus, external threats include: lack of a clear concept, strategy and program of socio-economic development with realistically achievable goals or too populist in nature; permanent lag in development, inconsistency and imperfection of regulatory and legal support for economic regulation; too risky monetary policy of the state in the banking sector, in the stock and foreign exchange markets, inefficient tax system, etc. The internal factors of economic security of economic entities arising in the sphere of its economic activity include: violation of the regime of preservation of confidential information; selection of unreliable partners and investors; outflow of qualified personnel; inability to objectively assess the qualifications of staff and their competence; insufficient patent protection; significant miscalculations in tactical and strategic planning, associated with incorrect assessment of the company's capabilities, errors in forecasting the environment, etc. The main components of economic security of economic entities were considered. Different definitions of economic security of the organization based on different approaches are systematized. The concept of "economic security" is clarified and formulated.

The purpose of the scientific research was to examine the essence and content of the modern human-centered concept in the theoretical-applied interpretation of management activities of state authorities, in connection with the implementation and protection of fundamental rights and freedoms of persons with systemic disorders of body function. The following research methods were used in the scientific work: systematization, generalization; analysis and synthesis of the developed ideas. Definitely, it is substantiated that significant reform changes in the system of state authorities of Ukraine and changes in the direction of their activities somehow mean the creation of conditions for the construction of a democratic, social and legal state, as well as the guarantee of subjective rights, in particular of persons with disabilities. The conclusions argue the priority of the formation of administrative and legal doctrine, built on the basis of a humanistic ideology that permeates the Convention on the Rights of Persons with Disabilities in the daily life of society as a whole.