Background: Volume deficit is one of the predictors of hypotension. Inferior venacaval collapsibility index (IVCCI) can detect volume deficit and aids volume resuscitation in patients of intensive care unit. Aims: The primary aim was to compare the incidence of postspinal anesthesia hypotension (PSAH) in IVCCI measured and nonmeasured groups. The secondary aim was to determine IVCCI association with PSAH within IVCCI measured group in spite of fluid bolus. Settings and Designs: This was a prospective, randomized, controlled, single-blinded study. Methodology: One hundred patients posted for orthopedic surgery under spinal anesthesia (SA) were randomly divided as IVCCI measured (CI) and non-IVCCI measured (NCI) groups before SA. If IVCCI was more than 40% fluid bolus was given. Intraoperative hemodynamics was monitored. PSAH managed with fluids and vasopressors which were noted. Data collected were analyzed with unpaired t-test, Z-test, logistic regression test, and Pearson's correlation. Results: PSAH incidence was 18% in group (CI) whereas 38% in group (NCI), and the difference was statistically significant. Vasopressors given were higher in group NCI. Perioperative fluids were more in group CI, but the intraoperative fluids were more in group NCI. There was no statistically significant association between PSAH after fluid preloading and IVCCI within the IVCCI measured group. Conclusion: Prespinal anesthesia evaluation of IVCCI to optimize fluid therapy can reduce the incidence of PSAH in orthopedic surgeries and the vasopressor requirement, and hence, the association of IVCCI of more than 40% with PSAH.

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