Exposure to mycotoxins occurs worldwide, even though there are geographic and climatic differences in the amounts produced and occurrence of these substances.Mycotoxins are secondary chemical metabolites of different fungi. They are natural contaminants of cereals, so their presence is often inevitable. Among many genera that produce mycotoxins, Fusarium fungi are the most widespread in cereal-growing areas of the planet. Fusarium fungi produce a diversity of mycotoxin types, whose distributions are also diverse. What is produced and where it is produced is influenced primarily by environmental conditions, and crop production and storage methods. The amount of toxin produced depends on physical (viz., moisture, relative humidity, temperature, and mechanical damage), chemical (viz., carbon dioxide,oxygen, composition of substrate, insecticides and fungicides), and biological factors (viz., plant variety, stress, insects, spore load, etc.). Moisture and temperature have a major influence on mold growth rate and mycotoxin production.Among the most toxic and prevalent fusaria) toxins are the following: zearalenone,fumonisins, moniliformin and trichothecenes (T-2/HT-2 toxin, deoxynivalenol,diacetoxyscirpenol, nivalenol). Zearalenone (ZEA; ZON, F-2 toxin) isaphy to estrogenic compound, primarily a field contaminant, which exhibits estrogenic activity and has been implicated in numerous mycotoxicoses of farm animals,especially pigs. Recently, evidence suggests that ZEA has potential to stimulate the growth of human breast cancer cells. Fumonisins are also cancer-promoting metabolites,of which Fumonisin 8 I (FBI) is the most important. Moniliformin (MON) isalso highly toxic to both animals and humans. Trichothecenes are classified as gastrointestinal toxins, dermatotoxins, immunotoxins, hematotoxins, and gene toxins.T-2 and HT-2 toxin, and diacetoxyscirpenol (DAS, anguidine) are the most toxic mycotoxins among the trichothecene group. Deoxynivalenol (DON, vomitoxin) and nivalenol although less toxic are important because they frequently occur at levels high enough to cause adverse effects.The presence of mycotoxins in the animal diet can produce significant production losses. Any considerable presence of mycotoxins, in major dietary components,confirms the need to adopt a continuous prevention and control program. Such programs are usually based on several common approaches to minimize mycotoxin contamination in the food chain. Major strategies include preventing fungal growth and therefore mycotoxin formation, reducing or eliminating mycotoxins from contaminated feedstuffs, or diverting contaminated products to low risk uses. Because of the complexity of their chemical structures, mycotoxins also present a major analytical challenge. They are also found in a vast array of feed matrices. Analysis is essential for determining the extent of mycotoxin contamination, for risk analysis, confirming the diagnosis of a mycotoxicosis and for monitoring mycotoxin mitigation strategies.For the future, adequately controlling the myc...
Seeking useful biological agents for mycotoxin detoxification has achieved success in the last twenty years thanks to the participation of many multidisciplinary teams. We have recently witnessed discoveries in the fields of bacterial genetics (inclusive of next-generation sequencing), protein encoding, and bioinformatics that have helped to shape the latest perception of how microorganisms/mycotoxins/environmental factors intertwine and interact, so the road is opened for new breakthroughs. Analysis of literature data related to the biological control of mycotoxins indicates the ability of yeast, bacteria, fungi and enzymes to degrade or adsorb mycotoxins, which increases the safety and quality of susceptible crops, animal feed and, ultimately, food of animal origin (milk, meat and eggs) by preventing the presence of residues. Microbial detoxification (transformation and adsorption) is becoming a trustworthy strategy that leaves no or less toxic compounds and contributes to food security. This review summarizes the data and highlights the importance and prospects of these methods.
Sturgeon aquaculture is economically important in many countries, for both meat and caviar production. Sturgeon is the common name for 27 species of fish belonging to the family Acipenseridae. Among them, only the sterlet (Acipenser ruthenus) and the Siberian sturgeon (Acipenser baerii) completes the lifecycle in fresh water. In Serbia, in the last few years, aquaculture enterprises have shown more interest in farming these fish species. Also, the importance of sturgeon aquaculture grows due to the rapid decrease of wild populations caused by overfishing, water pollution and destruction of habitat. The development of sturgeon aquaculture activities has been accompanied by the disease outbreaks, and possibility of the emergence and rapid dissemination of several infectious disease agents may represent serious problem in sturgeon aquaculture. Several viral, bacterial, fungal and parasitic diseases have been reported worldwide. Due to the limited knowledge about epizootiology and disease control methods, infectious diseases may represent a major challenge in sturgeon aquaculture. Moreover, none of the diseases reported in sturgeon are regulated in the World Organization for Animal Health (OIE) or European Union (EU) legislations. Due to the increasing interest in sturgeon aquaculture in Serbia present study is focused on the most important pathogens that may represent a threat to sturgeon aquaculture in Serbia.
Insect use in feed and food in European countries is now an increasingly debated topic, although these animals have traditionally been nutritional components in Asian, African, Central American and South American cultures. This review addresses the issue of eating insects and using them as feed components, especially considering the nutritionally important factors. Safety risks are also discussed, as well as allergies, toxicity, consumer acceptance, legislative, welfare and environmental concerns and possibilities for laboratory control. Insects play and will play important roles in the future in various fi elds of research and utilisation, but especially and increasingly as feed and food ingredients.
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