The business has a unique function in sustainable economic growth since it not only helps realize creative potential but also generates dispersed employment opportunities and additional funding for budgets at various levels. The use of various digital technologies within a business model that enables a company to have a variety of value-producing opportunities within the company is referred to as digitalization. Additionally, the field of management accounting has seen a significant degree of change with the aid of digitalization, which has improved it significantly. Furthermore, digitalization can have an impact on an organization's business models, and it enhances management accounting in a company setting. According to Business Trends in the Digital Era, trends drive transformations. Cities with greater competitiveness will transition from industrial centers to industry and innovation hubs, and businesses with greater competitiveness will transition from production to product and innovation centers. The secret to success is innovation! The current trend in development is innovation-driven. This article summarizes all the new trends of business in this digital era.

The approaches and methods used in qualitative and quantitative research represent various research strategies and have diverse theoretical, epistemological, and ontological concerns. Every strategy will depend on how the researchers gather and analyze their data. It is important to use caution when doing research on problem-solving lessons in secondary scientific education to prevent bias in the collection and interpretation of data. Despite the fact that both methods are employed by academics, the quantitative technique is more popular because of its strengths and qualities. To measure actions, views, attitudes, and other characteristics and draw generalizations from a larger population, quantitative research is utilized. In order to express facts and identify trends in study, quantitative research uses quantifiable data. When conducting this kind of research, results are derived using statistical and mathematical tools. This review article focuses on the basic terminologies of quantitative research, its applications in various sectors and reasons why quantitative research approaches surpass qualitative research methods.

Juvenile polyposis syndrome (JPS) is an autosomal dominant predisposition to the occurrence of hamartomatous polyps in the gastrointestinal tract. Diagnosis of JPS is based on the occurrence of numerous colon and rectum polyps or any number of polyps with family history and, in the case of juvenile polyps, their occurrence also outside the large intestine. The JPS is caused by mutations in SMAD4 and BMPR1A. Products of the SMAD4 gene are involved in signal transduction in the transforming growth factor β pathway and BMPR1A protein is a receptor belonging to the family of transmembrane serine/threonine kinases. Both proteins are responsible for processes determining appropriate development of colonic mucosa. The JPS belongs to the group of hamartomatous polyposes. The hamartomatous polyposis syndromes constitute a group of diseases in which manifestations differ slightly and only molecular diagnostics gives the possibility of verifying the clinical diagnosis.