Our data suggest that acemannan could be a candidate biomolecule for periodontal tissue regeneration.

Metallic implants are frequently used for stabilization of fractures in dogs and cats. Postoperative bacterial osteomyelitis is a recognized complication following fracture repair and can be influenced by the presence of metallic implants. Metallic implants influence susceptibility to infection through several mechanisms, including corrosion, adherence of biofilm, isolation from the immune response, and compromise of blood supply. Factors that should be considered when using metallic implants include antibiotic prophylaxis, appropriate implant selection, meticulous surgical technique and proper aseptic technique.

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Soontornvipart K., P. Kohout, P. Proks: Septic Arthritis in Dogs: A Retrospective Study of 20 Cases (2000Cases ( -2002. Acta Vet. Brno 2003, 72: 405-413. Septic arthritis might be difficult to diagnose due to nonspecific clinical signs and radiological findings in early stage of the disease. An early diagnosis is important for achieving favorable prognosis. Diagnosis of septic arthritis was confirmed by physical and orthopedic examinations, evaluation of radiographs and synovial fluid analysis including leukocyte and neutrophil counts, cytological examination and bacterial culture. Sensitivity and specificity of these diagnostic methods were retrospectively evaluated from clinical records of 18 dogs with 20 septic joints treated in the Department of Surgery and Orthopaedics in Small Animal Clinic at University of Veterinary and Pharmaceutical Sciences Brno from January 2000 till the end of 2002.Our patients affected by septic arthritis belonged to medium to large breed dogs. Infection of 13 septic joints in 11 patients was spread by hematogenous route, whereas the other 7 joints (in 7 patients) were infected during surgical procedure or after joint injury. Recurrence of hematogenous joint infection was found in 2 patients. In all the patients, exercise intolerance and painful reaction in affected joint were detected. Cultures of synovial fluid samples were positive in only 8 cases. Staphylococcus intermedius, Streptococcus spp., Enterococcus Group 3, Pseudomonas aeruginosa, coagulase-negative staphylococcus and Bacillus spp. were isolated. Radiographic findings included joint effusion, osteoarticular destruction and new bone proliferation and these were not specific for septic arthritis.We found that diagnostic methods used in this study showed high sensitivity but low specificity. Complex diagnostic approach including physical, orthopaedic and radiographic examinations, and synovial fluid evaluation should be performed to achieve correct diagnosis and effective treatment.