Introduction: Pain is a common postoperative complication. The ideal postoperative analgesia is awake, safe, mobile, and without side effects. The objective of this study is to provide new ideas for postoperative analgesia by observing the safety and analgesic effect of different analgesic methods in patients undergoing laparotomy after surgery. Methods: Patients, who underwent laparotomy between September 2019 and December 2020, were randomly divided into three groups: group S received sufentanil, group N received nalbuphine, group T ? N received postoperative bilateral transversus abdominis plane block (TAPB) and nalbuphine. The primary outcomes included visual analog scale (VAS) score and the use of postoperative analgesic pump. Secondary outcomes included quality of life recovery (QoR-15) scale score and incidence of postoperative adverse reactions. Results: Compared with group S and N, there were significant differences in the resting VAS score within 48 h after surgery, dynamic VAS score within 12 h after surgery, the first compression time, and cumulative use of patientcontrolled intravenous analgesia (PCIA) drugs at 24 h in group T ? N (P \ 0.05). The QoR-15 score within 48 h after surgery in group T ? N was significantly higher than group N (P \ 0.05). The first exhaust time and the incidence of nausea and vomiting in group T ? N were significantly lower than those in group N (P \ 0.05). Conclusions: Sufentanil PCIA and nalbuphine PCIA have equivalent analgesic effects, while TAPB combined with nalbuphine PCIA can ensure a good analgesic effect, thereby reducing the incidence of adverse reactions.

Introduction Complete postoperative analgesia is very important for puerperae after cesarean section. The objective of this study was to explore the optimal postoperative analgesia after cesarean section. Methods A total of 180 full-term puerperae who underwent cesarean section in Hanzhong People's Hospital from March 2019 to March 2020 were enrolled and were randomly divided into three groups. Group A was given 0.9% normal saline, group B and C were given 0.4% ropivacaine for transversus abdominis plane block (TAPB). Postoperative patient-controlled intravenous analgesia (PCIA) pumps were 2 μg/kg sufentanil + 2.5 mg droperidol, 1.5 μg/kg and 1.3 μg/kg sufentanil, respectively. All puerperae were given different but effective analgesia programs. The primary outcome indicators were visual analog scores (VAS), the first compression time of postoperative analgesia pump and the total number of compressions in 48 h. The secondary outcome indicators were vital signs, Ramsay sedation scores, comfort scores (BCS), the frequency of analgesic rescue, postoperative side effects and satisfaction. Results The dynamic and static VAS scores of the puerperae in group B at T 2 and T 6 were significantly lower than group A and at T 12 , T 24 and T 48 were significantly lower than group C. Compared with group A, the dynamic and static VAS scores of puerperae in group C were lower at T 2 and T 6 and higher at T 12 , T 24 and T 48 . The Ramsay score and BCS score of the puerperae in group C at T 12 , T 24 and T 48 were significantly lower than those in groups A and B. Conclusions PCIA with sufentanil alone or combined with TAPB can be safely and effectively used for postoperative analgesia after cesarean section. PCIA combined with TAPB had better analgesic effect and lower incidence of side effects while reducing the dose of opioids. The results of this study provide new ideas and insights for the choice of analgesia after cesarean section.

When a vehicle moves underwater, disturbance is generated and a wake remains that destroys the original free surface and produces a new wake. In order to study the mechanism and characteristics of the wave-making wake generated by the maneuvering motion of an underwater vehicle in density-stratified fluid, the k-ε model and the VOF method that is based on the RANS equation were used in this paper to analyze the SUBOFF model in stratified fluid at different drift angles. Numerical simulation of the maneuvering motion was carried out under these angles, and the corresponding changes in flow field caused by this motion were analyzed. The results from the comparison and analysis of the surface wave wakes under different drift angles in stratified fluid show that with the increasing drift angle, the motion wake of the vehicle still exhibits obvious Kelvin wave system characteristics. However, there are significant changes in hydrodynamic performance. The asymmetry of the surrounding flow field will increase with the increase in the drift angle. The pressure of the underwater vehicle is inversely proportional to the velocity of the surrounding flow field, and the amplitude of the peak and trough of the free surface wave is linearly related to the change in the drift angle. The numerical simulation can serve as a reference for the non-acoustic detection of the motion heading of an underwater vehicle and the motion trajectory of anti-reconnaissance underwater vehicles under actual sea conditions.

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Background Nowadays, liver transplantation has become a main therapy for end-stage liver disease. However, studies show that there are high mortality and severe complications after liver transplantation. Although gastrointestinal dysfunction is a common and major complication after liver transplantation, there was rarely relative research. This study aims to elucidate the factors about ileus after liver transplantation and patients’ survival. Methods We collected and analyzed the data (n = 318, 2016–2019) from the First Affiliated Hospital of Xi’an Jiaotong University. After excluding cases, a total of 293 patients were included for this study. The subjects were divided into a non-ileus group and an ileus group. We reviewed 38 variables (including preoperative, operative and postoperative relative factors). Additionally, other complications after liver transplantation and survival data were compared between two groups. Results Of the 293 patients, 23.2% (n = 68) experienced postoperative ileus. Ileus patients were not different with non-ileus patients in preoperative, operative and postoperative factors. HBV-positive patients with ileus had a lower MELD score (P = 0.025), and lower postoperative total bilirubin was correlated with ileus (P = 0.049). Besides, Child–Pugh score of HCC patients with ileus was low (P = 0.029). The complications after liver transplantation were not different between two groups. Compared with the patients without ileus, the patients with ileus had a higher mortality rate. Conclusion According to our research, ileus-patients had a lower 1-year survival rates. The preoperative MELD score and postoperative total bilirubin of HBV-positive patients with ileus were lower, and Child–Pugh score of HCC patients with ileus was also lower.