Background: Adenoidectomy is currently considered the treatment of choice for children with severe symptoms caused by Adenoids Hypertrophy (AH). Non-surgical alternative treatment options are considered in less severe cases to avoid the untoward effect of surgery. This study was aimed to evaluate the efficacy and safety of Mometasone Furoate nasal spray combined with Montelukast Sodium in children with AH.
Materials and methods: This trial included 118 patients aged 3 to 13 years having symptomatic AH from the OPD of Otolaryngology and Head Neck Surgery of CMCH from May 2019 to April 2020. They were allocated to either Mometasone Furoate nasal spray combined with Montelukast Sodium (Group A: 59) or Mometasone Furoate nasal spray alone (Group B: 59) randomly for 8 weeks. Outcome measures were changes in the severity of symptoms and changes in the adenoid size from baseline. Out of 118 enrolled children, 109 children completed the study per protocol.
Results: The mean total clinical symptom score before and after treatment in group A was respectively 10.04 (±1.78) and 4.92 (±1.65). In group B the corresponding figures were respectively 9.42 (±1.33) and 5.48 (±1.36). Clinical symptom scores as well as Adenoidalnasopharyngeal ratio dropped significantly in both groups without any statistical significance between two groups with 8 weeks of treatment.
Conclusion: Mometasone Furoate nasal spray with and without oral Montelukast Sodium showed similar efficacy in symptom alleviation and adenoid size reduction without any superiority of combination therapy.
JCMCTA 2021 ; 32 (2) : 59-63
Thyroid cancer is the most common endocrine malignant lesion and its incidence continues to rise. The aim of this study was to assess association between thyroid antibodies and thyroid malignancies. This was a cross sectional study of 120 patients with thyroid nodules undergoing thyroidectomy with recorded preoperative thyroid antibodies [autoantibodies to thyroglobulin (TgAb)
Background : To see effectiveness of Endoscopies sinus surgery and it’s complication for the management of maxillary antral diseases. Materials and methods : A cross sectional observational study conducted from August’2014 to February’2016 in Otolaryngology Department, Chittagong Medical College Hospital, Chittagong. Results : The age of majority of the patients range from 21-30 years. Male and female patients were equal in number (M.F=1.1). The presenting symptoms of the patients were nasal obstruction, nasal discharge, headache, post nasal space drip, smell disturbance, recurrent sore throat and epistaxis. Major indications were chronic maxillary sinusitis 14 (46.67%), antrochoanal polyp 9(30%). Minor complication occurred in 9(30%) cases which included synechiae 3(10%) epistaxis 3(10%) and periorbital echymosis 3 (10%). Conclusion : No serious complications like CSF leak, retro orbital hemorrhage, blindness were noted.
JCMCTA 2017 ; 28 (1) : 27 - 31
Background : Oral malignancy is an emerging disease all over the world. Treatment failure is grave if the diagnosis is delayed in this disease which will ultimately increase the mortality rate. This is an observational sociodemographic study, done to identify the causes in diagnostic delay of the patients suffering from oral cancer.
Materials and methods: The study was done with a sample size of 215 cases of oral cancer patients. This observational study was conducted from 1st August 2015 to 31st December 2016 at Upazila Health Complex, Mirsarai, Chattogram & later at ENT Department of Chittagong Medical College Hospital from 1st March 2017 to 30thApril 2018.
Results: Several causes of diagnostic delay were identified. Among them, monetary issue (78%) and Ignorance or Illiteracy (69%) have been found as the most important causes. Stage of the disease, delay in referral system, tobacco use, age, gender, alternative medicine, social taboo ,distance of hospital from house etc were found the other factors delaying the diagnosis of the cancer.
Conclusion: Many of the causes of delay can be preventable. The authority should establish awareness among the patients & a protocol for early detection of cancer by the health professionals.
Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 37-40
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