Background : Oral malignancy is an emerging disease all over the world. Treatment failure is grave if the diagnosis is delayed in this disease which will ultimately increase the mortality rate. This is an observational sociodemographic study, done to identify the causes in diagnostic delay of the patients suffering from oral cancer. Materials and methods: The study was done with a sample size of 215 cases of oral cancer patients. This observational study was conducted from 1st August 2015 to 31st December 2016 at Upazila Health Complex, Mirsarai, Chattogram & later at ENT Department of Chittagong Medical College Hospital from 1st March 2017 to 30thApril 2018. Results: Several causes of diagnostic delay were identified. Among them, monetary issue (78%) and Ignorance or Illiteracy (69%) have been found as the most important causes. Stage of the disease, delay in referral system, tobacco use, age, gender, alternative medicine, social taboo ,distance of hospital from house etc were found the other factors delaying the diagnosis of the cancer. Conclusion: Many of the causes of delay can be preventable. The authority should establish awareness among the patients & a protocol for early detection of cancer by the health professionals. Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 37-40

Background: Neck masses are found in all age groups from many causes, ranging from congenital to acquired pathology. There is a wide variation in the presentation of neck masses concerning its site of origin, clinical presentation, and the nature of the progression of the disease. This study was performed to have an idea about the prevalence of various neck masses according to age and sex so that it would help us in diagnosing the neck masses. Materials and methods: This retrospective study was performed in the Department of Otolaryngology and Head Neck Surgery, Chattogram General Hospital, Chattogram from July 2018 and June 2019, over 97 patients presented with neck mass.   Results: Of 97 cases 69.1% were female and range from 7-77 years. The maximum case holding age group was 21- 30 years (26.8%). The histopathological diagnosis of the neck masses was inflammatory in 68 (70.1%), congenital in 5 (5.2%) and neoplastic in 24 (24.7%) cases. Chronic granulomatous lymphadenitis was the most common inflammatory lesion (50.5%) and a branchial cyst was the most common congenital mass (2.2%). Neoplastic masses were malignant in 10 (10.3%) and benign in 14 (14.4%) cases. The most common malignant neoplastic mass was a follicular carcinoma (6.2%), and the most common benign neoplastic mass was goitre (12.4%).   Conclusions: Cervical lymphadenopathy was the most commonly encountered neck mass. Most of the neck masses are benign. Out of these cervical lymph nodes, tubercular lymphadenopathy was most common. JCMCTA 2022 ; 33 (1) : 21-24

Background: Adenoidectomy is currently considered the treatment of choice for children with severe symptoms caused by Adenoids Hypertrophy (AH). Non-surgical alternative treatment options are considered in less severe cases to avoid the untoward effect of surgery. This study was aimed to evaluate the efficacy and safety of Mometasone Furoate nasal spray combined with Montelukast Sodium in children with AH.  Materials and methods: This trial included 118 patients aged 3 to 13 years having symptomatic AH from the OPD of Otolaryngology and Head Neck Surgery of CMCH from May 2019 to April 2020. They were allocated to either Mometasone Furoate nasal spray combined with Montelukast Sodium (Group A: 59) or Mometasone Furoate nasal spray alone (Group B: 59) randomly for 8 weeks. Outcome measures were changes in the severity of symptoms and changes in the adenoid size from baseline. Out of 118 enrolled children, 109 children completed the study per protocol. Results: The mean total clinical symptom score before and after treatment in group A was respectively 10.04 (±1.78) and 4.92 (±1.65). In group B the corresponding figures were respectively 9.42 (±1.33) and 5.48 (±1.36). Clinical symptom scores as well as Adenoidalnasopharyngeal ratio dropped significantly in both groups without any statistical significance between two groups with 8 weeks of treatment. Conclusion: Mometasone Furoate nasal spray with and without oral Montelukast Sodium showed similar efficacy in symptom alleviation and adenoid size reduction without any superiority of combination therapy. JCMCTA 2021 ; 32 (2) : 59-63

Introduction: Cervical Intraepithelial Neoplasia is a precancerous condition in which abnormal cells grow on the surface of the cervix. CIN is a symptomless illness that often goes undetected by the naked eye. In most cases, the afflicted cervix appears to be in excellent health. As a result, the illness is detected by chance during cervicological histology or as a result of programs for routine cervical cytology or colposcopy screening. Colposcopy is an extra and valuable technique for identifying cervix anomalies. This study aimed to analyze the correlations between colposcopy findings and histopathological results from colposcopy-directed biopsy in cervical pre-cancerous lesions. Methods: A prospective observational study was conducted at the Department of Gynecology and Obstetrics, Chittagong Medical College Hospital, Chittagong, from September 2014 to February 2015. VIA-positive 72 women fulfilling all inclusion criteria who attended at colposcopy clinic of CMCH were included in the study. Statistical analyses were done by using the Statistical Package for Social Sciences (SPSS) version 16.0 for Windows. The quantitative observations were indicated by frequencies and percentages. Result: In the present study, the majority of the participants were over the age of 30 years, with 43.1% being in the age group of 30-39 years. Another 30.6% were from the age group of 40-49 years, while only 15.2% were from the age group of 20-29 years. Colposcopy findings were normal in 9.7% of the participants. CIN I was observed in the majority of the participants (54.2%), while CIN II and CIN III were observed in 29.2% and 6.94% respectively. According to the colposcopy-directed biopsy results, 5.6% of patients had normal outcomes, 7.7% had inflammations, 45.8% had CIN I, 30.6% had CIN II and 8.3% had CIN III. The correlation was calculated by reporting the number of cases histologically confirmed to the number of cases of colposcopic diagnosis for each lesion group separately. The correlation was 71.8% (28 out of 39) in the CIN I category, 76.2% (16 out of 21) in the CIN II category, and 75% (3 out of 4) in the CIN III category. The sensitivity and specificity of colposcopy were calculated considering a colposcopy-directed biopsy. Colposcopy findings revealed 65 CIN positive cases and 07 CIN negative cases, while biopsy findings revealed 60 positive and 12 negative cases. The sensitivity of colposcopy was 96.7%, specificity was 41.6%, the false positive rate was 58.4% and the false negative rate was 03.3% according to this study. Conclusion: This study demonstrated high accuracy and correlation between colposcopy and histology. The sensitivity of colposcopy was 96.7%, specificity was 41.6%, the false positive rate was 58.4% and the false negative rate was 03.3%. Specificity was lower in this study probably because biopsies were performed in all cases during diagnostic workups.

Background : To see effectiveness of Endoscopies sinus surgery and it’s complication for the management of maxillary antral diseases. Materials and methods : A cross sectional observational study conducted from August’2014 to February’2016 in Otolaryngology Department, Chittagong Medical College Hospital, Chittagong. Results : The age of majority of the patients range from 21-30 years. Male and female patients were equal in number (M.F=1.1). The presenting symptoms of the patients were nasal obstruction, nasal discharge, headache, post nasal space drip, smell disturbance, recurrent sore throat and epistaxis. Major indications were chronic maxillary sinusitis 14 (46.67%), antrochoanal polyp 9(30%). Minor complication occurred in 9(30%) cases which included synechiae 3(10%) epistaxis 3(10%) and periorbital echymosis 3 (10%). Conclusion : No serious complications like CSF leak, retro orbital hemorrhage, blindness were noted. JCMCTA 2017 ; 28 (1) : 27 - 31