Inadequate rheological properties of gelatin methacrylamide (GelMA) were successfully improved by incorporating cellulose nanofibers (CNFs), such that the printed scaffolds could maintain their structural fidelity during the three-dimensional (3D) bio-printing process. The CNFs provided an outstanding shear thinning property, and the GelMA/CNF inks exhibited high zero shear viscosity and structural fidelity under a low dispensing pressure. After evaluating the printability, composite inks containing 2% w/v CNF were observed to have an optimal concentration of CNF to prepare 3D print stable constructs. Therefore, these inks were used to manufacture human nose and ear structures, producing highly porous structures in the printed composite hydrogels. Furthermore, the mechanical stability of the GelMA/CNF composite hydrogel was increased when CNFs were incorporated, which indicated that CNFs played an important role in enhancing the structural properties of the composite hydrogels. Additionally, the biocompatibility of CNF-reinforced hydrogels was evaluated using a fibroblast cell line.

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This study examines the impact of gender at three different positions in a firm’s hierarchy on innovative activities, looking at over 6474 firms in 30 emerging countries. We create a dummy variable for each of the six survey questions on product innovation, process innovation, organizational innovation, marketing innovation, and R&D (Research & Development) spending. Each dummy acts as a dependent variable in a separate logit regression, and the sum of the dummies acts as the dependent variable in another ordered logit regression. We use the female ownership percentage, female top management, and female majority in the workforce as test variables. We use the Heckman two-stage model to address endogeneity concerns with gender. We find that the female ownership percentage is generally positively related to individual innovation measures as well as the composite measure, while female top management is positively associated with marketing innovation only, and a female majority in the workforce is not significantly related to any measure. The results suggest that promoting innovation in emerging countries would involve governments encouraging further market participation by women and supporting female CEOs (Chief Executive Officers) to innovate, and firms fostering innovation among female workers.

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