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This study evaluates the hypothesis that the decreased reaction to ethanol reported for sons of alcoholics will also be observed following infusions of a benzodiazepine. The investigation compared 37 men who were family history positive for alcoholism with 37 family history negative controls on postinfusion levels of cortisol, prolactin, and growth hormone following 0.12 and 0.20 mg/kg of diazepam given IV over 7 minutes. The results demonstrated no evidence of a decreased response for the sons of alcoholics on the levels of these three hormones.

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This trend remained the same for both viral and bacterial URTIs. Patients from less deprived households were less likely to be discharged and more likely to be admitted, for both short (< 24 hours) and longer admissions (> 24 hours). Mapping of patient postcodes highlighted 'hotspots' of patients in the North East. Conclusion There is a significant relationship between social deprivation and presentation to Paediatric A&E with URTI in the North East. Most patients presenting to Great North Children's Hospital Paediatric A&E with URTI came from more socially deprived backgrounds.