Leptospirosis is a common worldwide zoonotic infection, is an important livestock problem throughout Ukraine. The peculiarities of leptospirosis are the presence of more than 250 serological groups of the pathogen, which significantly influences the choice of strategy for prevention and control of this disease. The article presents data on the epizootic situation, the epizootological features of leptospirosis and the etiological structure of leptospiras in cattle in Vinnitsa region (1994-2015) and, in particular, in the farms of the Khmelnitsky district (2006-2012). The epizootic situation with leptospirosis of cattle in Vinnitsa region and the farms of Khmelnytsky district is characterized by certain fluctuations in the number of infections points and sick animals, with relative stability. Tottaly 247 cattle farms infections of leptospirosis were identified in the region during 21 years. The materials for the research were the data of veterinary records and reports of farms and state veterinary medicine establishments of Vinnitsa region, the results of laboratory tests of blood serum from cattle from suspicious farms, the results of the analysis of health and preventive measures in suspicious farms. The main leptospira serogroups that affect cattle in Vinnytsa region and directly in the Khmelnitsky region were Hebdomadis, Sejroe, Icterohaemorrhagiae, Grippotyphosa, Pomona, registered from 43 to 86.3% of mixed reactions. In Khmelnytsky district in 2006-2012, 7 infected farms were registered, 739 animals got sick. It was established that the epizootic situation in the farms depended on the observance of preventive and sanitary measures and the timely introduction of recovery plans. It has been proved that the integrated use of veterinary, sanitary and economic measures is an effective means of eliminating and preventing cattle leptospirosis in livestock farms. The complex of measures should include timely serological analisis of cattle on leptospirosis, adherence to quarantine during importation of animals to the herd, sanitary and preventive measures of exploitation of animals, vaccination of cattle against leptospirosis, taking into account the etiological structure of the disease. Key words: leptospira, leptospirosis, cattle, microscopic agglutination test (MAT), leptospira serological groups, epizootic situation.

Інститут ветеринарної медицини НААН 2 Державний науково-дослідний інститут з лабораторної діагностики та ветеринарно-санітарної експертизи РОЗПОВСЮДЖЕННЯ ХВОРОБИ АУЄСКІ СЕРЕД ПОГОЛІВ'Я ДИКИХ КАБАНІВ НА ТЕРИТОРІЇ УКРАЇНИ ЗА 2010-2019 РР.

Herpesvirus mamilit in cattle is a viral disease characterized by vesicular, erosive and necrotic lesions of the skin of the nipples and udder. Currently, there are two forms of this disease, PSLD (pseudo-lumpy skin disease) and BHM (bovine herpetic mamilit).The first report on the isolation of herpesvirus from cattle with dermatitis (strain Allerton) dates back to 1957, when in South Africa diseases were observed among cows with lumpy dermatitis with ulcerative damage to the skin of the udder nipples. Later, in the 60s of the last century, there were reports of cases of ulcerative mamilitis of viral etiology among cows in Bulgaria, Australia and in the countries of South Africa -Rwanda and Tanzania. In all cases of herpesvirus mamilitis, the causative agent of the disease was identified as herpesvirus of the 2nd serotype. The herpesvirus etiology of the disease was also laboratory confirmed in the Netherlands, Switzerland, Ireland, Germany and the Czech Republic.In Ukraine, the first report of herpesvirus mamilitis of cattle (ulcerative mamilitis of cows) appeared only in 2003, although diseases with similar clinical signs were known earlier.Infection of dairy cattle can significantly affect productivity (decrease by about 20 %), chronic mastitis arising from this disease leads to a decrease in the number of productive animals. Natural infection caused by BoHV-2 occurs mainly in heifers and first lactation cows. Calving can be a factor in the reactivation of the virus. The natural transmission mechanism of the BoHV-2 virus is not fully understood. Most people talk about mechanical transmission through milking machines, through attendants, through the bites of Stomoxys calcitrans flies. The intact nipple skin is resistant to the penetration of the virus, which proves once again that any nipple injury is preceded by an infection.Serological studies show that the virus is common in livestock throughout the world. According to clinical signs, it is rather difficult to differentiate this disease from other viral diseases (viral diarrhea, malignant catarrhal fever, parapoxviruses, infectious rhinotracheitis in cattle). The specialist literature describes the treatment of BoHV-2 disease in cows. The authors used Intacef for injection (Intas pharma, 3 g i / m), anistamine for injection (10 ml i / m), Melonex (10 ml i / m). Udder ulcers were treated with povidone-iodine ointment twice daily for 5 days. On the 5th day of treatment, the animals recovered.Vaccines for specific prevention of this disease have not been developed. Sick animals are separated (if possible) from the general herd and treated. Clinically affected animals are milked last. The udders and teats should be disinfected to reduce the spread of the virus. It is imperative to disinfect the milking machines and hands after each cow and after milking. The udder skin should be monitored to prevent mastitis.The widespread spread of this disease among productive animals, significant economic losses in the form of reduced milk yield and treatment costs, and the d...

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