The worsening of endothelium dependent vasodilation, antioxidate protection and increasing aggregation of platelets at children and adolescens with vegetative dysfunction and risk factors of atherosclerosis (n = 136) in contrast with given factors in the group healthy children and teenagers (n = 190) were revealed. The elimination of changing risk factors of atherosclerosis (smoking, stress, hypodynamia, atherogenic diet, etc) alongside traditional treatment with 12 monthes of rehabilitation the ill children the studing parameters at low and average level of the risk factors of atherosclerosis normalized and only partial сhanged at high level one.