Brazil is the biggest country in South America, with more than 207 million of inhabitants. From them, 15% of the population is in primary and high schools. The worldwide KIDS SAVE LIVES campaign 1-3 was first implemented in Brazil as KIDS SAVE LIVES BRAZIL by a group of associate professors, researchers and graduate students from multidisciplinary areas of University of São Paulo. KIDS SAVE LIVES BRAZIL program sought to train school community as all citizens can save a life 4 to know, to identify and to
The frequencies of chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) were determined in peripheral blood lymphocyte cultures from women with breast cancer treated by chemotherapy (CT) with FEC (5-fluorouracil, epirubicin, and cyclophosphamide) or CMF (cyclophosphamide, methotrexate, and 5-fluorouracil) cocktail in six CT cycles. The number of patients in each CT cycle were from 1 to 3 for SCE and 2 to 5 for CA. Samples were collected before and 48 h after CT. Although the size of the sample was limited and interindividual variability was wide, it appears that a 21-day interval between CT sessions is sufficient for cell recovery. This fact was demonstrated by the reduction in CA and SCE frequencies between cycles in parallel with the unchanged mitotic index and proliferative index values.
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