No abstract

After completing this course, the reader will be able to:1. Utilize data supporting the efficacy of low-dose definitive brachytherapy to inform clinical decisions about treating women with high-grade vaginal intraepithelial neoplasia.2. Implement methods for delivering low-dose definitive brachytherapy that minimize toxicity.3. Communicate to patients the type and incidence of toxic events associated with low-dose definitive brachytherapy.This article is available for continuing medical education credit at CME.TheOncologist.com. CME CME ABSTRACTBackground. Treatment of high-grade vaginal intraepithelial neoplasia (VAIN) is controversial and could include surgical excision, topical medication, brachytherapy, or other treatments. We report the results of low-dose-rate (LDR) vaginal brachytherapy for grade 3

This regimen is an alternative to conventional chemoradiotherapy with good response rates and acceptable toxicity for selected patients.

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