Study Objective: to investigate the association of dyspepsia and heartburn in school-age children. Study Design: A continuous epidemiological screening of heartburn and dyspepsia in school-age children was carried out using a single- point (transverse) method. Material and Methods. A total of 328 children were examined (163 boys and 165 girls, mean age 12.4 years). Heartburn was determined according to the recommendations of the international pediatric consensus on gastroesophageal reflux disease. Dyspepsia was diagnosed in accordance with the pediatric section of the Rome IV criteria. Study Results. The prevalence of dyspepsia syndrome was 14.0%, heartburn — 10.4%. Increasing age in children was a risk factor for dyspepsia. The frequency of heartburn was registered in 39.1% of patients with dyspepsia and only in 5.7% of those without dyspepsia (p < 0.001). The prevalence of overlap syndrome of dyspepsia and heartburn in school-age children was 5.5%. Conclusion. The association of heartburn and dyspepsia in school-age children is a real problem that requires the attention of practitioners. Keywords: gastroesophageal reflux disease, dyspepsia, overlap syndrome, children.
Objective of the Review: To analyze current data on eosinophilic lesions of the stomach in children with the analysis of a clinical case. Key points. Diseases of the gastrointestinal tract associated with primary tissue eosinophilia are a heterogeneous group of changes characterized by inflammation, with predominantly eosinophilic tissue infiltration in the absence of other known causes. Clinical manifestations of allergic inflammatory diseases of the gastrointestinal tract are most often nonspecific. Depending on the level of the lesion, eosinophils are distinguished: gastritis (EoG), enteritis, and colitis. In recent years, more and more attention of experts has been directed to research in this area, but so far there are no general epidemiological data on the prevalence of this pathology in the population, both adults and children. Conclusion. Currently, there are no clear morphological criteria for diagnosing eosinophilic lesions of the stomach, small and large intestine in children, and clinical manifestations, especially in young children, are nonspecific. When making a diagnosis of EoG, it is necessary to take into account a family allergic history, a set of laboratory diagnostic data (eosinophilia in a clinical blood test and a high level of total IgE) and a morphological study of a biopsy of the gastric mucosa. Keywords: children, eosinophilic gastritis, eosinophilia, tissue eosinophilia, food allergy.
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