We aimed to analyze the association between the distribution of dendritic cells (DC) with expression of tumor-infiltrating T lymphocytes and clinicopathologic parameters with prognosis in epithelial ovarian cancer (EOC). Thirty-three EOC patient samples were surgically resected, and pathology was examined for clinicopathological variables. Expression of S-100, CD1a, CD45RA and CD45RO was detected using the avidin-biotin complex immunohistochemical technique. The correlation of protein expression with surgical and pathological stage, histological grade, pathological type and prognosis was analyzed. There was significant difference in the CD45RA positive rate in early- and advanced-stage EOC with 50 and 10.5%, respectively (P<0.05). Univariate analysis showed that CD45RO, histological grade and surgical-pathological staging were all factors that influenced the prognosis of patients with EOC. Higher survival rates were found in patients with harboring populations of CD1a(+) DC and CD45RO(+) T lymphocytes or populations of S-100(+) DC and CD45RO(+) T lymphocytes (P<0.05). In addition, histological grade is related to cumulative survival rate. The higher degree of cell differentiation presented better outcome. In conclusion, EOC patients with populations of DC and CD45RO(+) T lymphocytes had a higher survival rate. Histological grade and surgical-pathological stage were independent factors affecting prognosis.

Objective To differentiate gastric leiomyomas (GLs) and gastric stromal tumors (GSTs) based on preoperative enhanced computed tomography characteristics. Methods Twenty-six pathologically confirmed GLs were propensity score-matched to 26 GSTs in a 1:1 ratio based on sex, age, tumor site, and tumor size. Tumor shape and contour, mucosal ulceration, growth pattern, enhancement pattern and degree, longest diameter, and longest diameter/vertical diameter ratio were compared between the groups. Hemorrhage, calcification, peripheral invasion, and distant metastasis were also included in the regression analysis for differentiation of the two tumors. Results Mucosal ulceration was significantly more frequent in GSTs than GLs. The enhancement degree of GSTs was significantly higher than that of GLs in the arterial and portal venous phases. Using enhancement degrees of 18 HU and 23 HU in the arterial phase and venous phase as cutoff values, respectively, we found that an enhancement degree of <18 HU in the arterial phase was an independent influential factor for diagnosis of GLs. No significant differences were found in other morphological characteristics. GLs did not metastasize or invade adjacent tissues. Conclusion A low enhancement degree in GLs is the most valuable quantitative feature for differentiating these two similar tumors.

Purpose: To measure the setup errors with infrared marker‐based positioning system (IM‐BPS) and electronic portal imaging device （EPID） for patients with esophageal carcinoma and lung cancer and investigate the accuracy and practicality of IM‐BPS. Methods: From January 2007 to January 2008, 40 patients with esophageal carcinoma and 27 patients with lung cancer received three‐dimensional conformal radiotherapy or intensity‐modulated radiotherapy, setup errors during the treatment were measured with IM‐BPS and EPID, and the data of setup errors were compared with paired t‐test and agreement with χ2‐ test. Results: ⑴It takes 10–12mins to complete the validating for each patient by EPID system, while IM‐BPS system only needs 2–5mins. ⑵The mean setup errors along x‐axis, y‐axis, z‐axis for patients with esophageal carcinoma measured by IM‐BPS and EPID were 3.49mm, 3.19mm, 3.31mm and 4.03mm, 3.41mm, 3.43mm, respectively. For the patients with lung cancer, the setup errors were 4.23mm, 3.51mm, 3.39mm and 4.85mm, 3.53mm, 3.74mm, respectively. ⑶The difference of setup errors measured by the two systems was within 1mm for 65% esophageal carcinoma patients (χ2=51.09，P=0.000), the difference of setup errors measured by the two systems was within 1 mm for 55% lung cancer patients (χ2=53.35,P=0.000). ⑷The rotation errors along sagittal plane, coronal plane and transverse plane for patients with esophageal carcinoma and lung cancer measured by IM‐BPS were 0.31o, −0.90o, 0.34o and 0.05o, −1.12o, 0.22o, respectively. Conclusions: The measurement results of setup errors for patients with esophageal carcinoma and lung cancer show that IM‐BPS is mostly better than EPID. Though validating for patients can be measured accurately and be well quality controlled, IM‐BPS is used easily because of macroscopic, homely, spare time and real‐time monitoring.

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