The cross-sectional study aimed to investigate the relationship between the domains of perceived social support (PSS), perceived control of internal states (PCOIS) and well-being (WB) among police personnel. One hundred twenty two police officers (106 males and 16 females) from the state of Odisha, India were selected using purposive sampling method and were required to fill up the perceived social support, perceived control of internal states and well-being questionnaires. The relationships among these variables were examined using Pearson product moment correlation. The impact of social support and perceived control of internal states on well-being was analysed by multiple hierarchical regression analysis. Significant positive relationships among all these variables were noted. The relationship between the social support from friends’ domain and well-being was not significant. In addition, well-being was predicted by both perceived social support and perceived control of internal states. The findings of this study can help in developing interventions which can enhance the well-being of police personnel by targeting their perceived social support and perceived control of internal states.